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Tbio
VWA5A
von Willebrand factor A domain-containing protein 5A

Protein Summary
Description
May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361352
  • ENSP00000355070
  • ENSG00000110002
  • ENST00000392748
  • ENSP00000376504
  • ENST00000449321
  • ENSP00000404683
  • ENST00000456829
  • ENSP00000407726

Symbol
  • BCSC1
  • LOH11CR2A
  • BCSC1
  • BCSC-1
  • LOH11CR2A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.99
transcription factor perturbation
0.8
histone modification site profile
0.78
kinase perturbation
0.76
small molecule perturbation
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.21   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 309   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.21   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 309   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Protein-Protein Interactions (45)
1 – 10 of 45
MCM9
Tbio
Family: Enzyme
Novelty: 0.0390791
p_int: 0.999983665
p_ni: 0.000016333
p_wrong: 2e-9
Score: 0.313
Data Source: BioPlex,STRINGDB
CREBZF
Tbio
Family: TF
Novelty: 0.06925638
p_int: 0.999965666
p_ni: 0.000015622
p_wrong: 0.000018712
Score: 0.189
Data Source: BioPlex,STRINGDB
MAN2C1
Tbio
Family: Enzyme
Novelty: 0.01159051
p_int: 0.999837954
p_ni: 0.0001616
p_wrong: 4.45e-7
Score: 0.21
Data Source: BioPlex,STRINGDB
PKNOX2
Tbio
Family: TF
Novelty: 0.02053794
p_int: 0.999817803
p_ni: 2.87e-7
p_wrong: 0.000181911
Score: 0.208
Data Source: BioPlex,STRINGDB
PBX3
Tbio
Family: TF
Novelty: 0.01516183
p_int: 0.999340858
p_ni: 0.000632144
p_wrong: 0.000026998
Score: 0.214
Data Source: BioPlex,STRINGDB
ARMCX3
Tdark
Novelty: 0.25544824
p_int: 0.999255505
p_ni: 0.000744495
Data Source: BioPlex
HIC2
Tbio
Family: TF
Novelty: 0.1544738
p_int: 0.999212526
p_ni: 0.000787474
Data Source: BioPlex
PTPN23
Tbio
Family: Enzyme
Novelty: 0.03578001
p_int: 0.998204227
p_ni: 0.001794617
p_wrong: 0.000001155
Score: 0.164
Data Source: BioPlex,STRINGDB
PBX1
Tbio
Family: TF
Novelty: 0.00329442
p_int: 0.99806611
p_ni: 0.00193389
Score: 0.275
Data Source: BioPlex,STRINGDB
ADD3
Tbio
Family: Enzyme
Novelty: 0.02164464
p_int: 0.9962841
p_ni: 0.0037159
Data Source: BioPlex
Publication Statistics
PubMed Score  12.21

PubMed score by year
PubTator Score  9.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer