You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
EFCAB3
EF-hand calcium-binding domain-containing protein 3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000305286
  • ENSP00000302649
  • ENSG00000172421
  • ENST00000450662
  • ENSP00000403932
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.75
gene perturbation
0.68
tissue
0.67
kinase perturbation
0.66
cell line
0.63


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.42   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.42   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 3
VGNC:9268
468288
Macaque
EF-hand calcium binding domain 3
717476
Mouse
MGI:1918144
70894
Rat
RGD:1305423
303589
Dog
EF-hand calcium binding domain 3
VGNC:40215
490916
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 3
Macaque
EF-hand calcium binding domain 3
Mouse
Rat
Dog
EF-hand calcium binding domain 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8N7B9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (25)
1 – 10 of 25
IQCF2
Tdark
Novelty: 12.69230769
Score: 0.812
Data Source: STRINGDB
MYH10
Tbio
Novelty: 0.00624251
Score: 0.634
Data Source: STRINGDB
OBSCN
Tbio
Family: Kinase
Novelty: 0.01173699
Score: 0.601
Data Source: STRINGDB
SPEG
Tbio
Family: Kinase
Novelty: 0.01666376
Score: 0.601
Data Source: STRINGDB
EFCAB13
Tdark
Novelty: 0.78221339
Score: 0.601
Data Source: STRINGDB
METTL2A
Tdark
Family: Enzyme
Novelty: 0.72443397
Score: 0.558
Data Source: STRINGDB
MARCH10
Tdark
Family: Enzyme
Novelty: 0.23101375
Score: 0.547
Data Source: STRINGDB
PAQR8
Tbio
Novelty: 0.05328888
Score: 0.537
Data Source: STRINGDB
PGBD5
Tdark
Novelty: 0.15960609
Score: 0.535
Data Source: STRINGDB
ZNF395
Tbio
Novelty: 0.07158931
Score: 0.517
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.42

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer