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Tbio
PHF14
PHD finger protein 14

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000403050
  • ENSP00000385795
  • ENSG00000106443

Symbol
  • KIAA0783
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
drug perturbation
0.96
transcription factor perturbation
0.91
histone modification site profile
0.83
ligand (protein) perturbation
0.83
microRNA
0.8


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.57   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.57   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
5.7
34.3
age at onset
1
1
0
5.7
34.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
5.7
34.3
age at onset
0
5.7
34.3
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
PHD finger protein 14
VGNC:4466
463265
Macaque
PHD finger protein 14
694855
Mouse
MGI:1923539
75725
Rat
RGD:1563764
500030
Dog
PHD finger protein 14
VGNC:44483
100686369
Species
Name
OMA
EggNOG
Inparanoid
Chimp
PHD finger protein 14
Macaque
PHD finger protein 14
Mouse
Rat
Dog
PHD finger protein 14
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O94880-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (32)
1 – 10 of 32
HIST1H2BA
Tbio
Novelty: 0.02431803
p_int: 0.999999945
p_ni: 5.3e-8
p_wrong: 1e-9
Score: 0.601
Data Source: BioPlex,STRINGDB
HMG20A
Tbio
Family: TF
Novelty: 0.11994252
p_int: 0.999999869
p_ni: 1.26e-7
p_wrong: 6e-9
Score: 0.746
Data Source: BioPlex,STRINGDB
H2AFZ
Tbio
Novelty: 0.00222512
p_int: 0.999999857
p_ni: 1.43e-7
Score: 0.343
Data Source: BioPlex,STRINGDB
H2AFX
Tbio
Novelty: 0.00048694
p_int: 0.999999118
p_ni: 8.81e-7
Score: 0.35
Data Source: BioPlex,STRINGDB
GSKIP
Tbio
Novelty: 0.07130117
p_int: 0.964671045
p_ni: 0.034322028
p_wrong: 0.001006927
Data Source: BioPlex
SPECC1L
Tbio
Novelty: 0.06116909
p_int: 0.957264106
p_ni: 0.042735893
p_wrong: 1e-9
Data Source: BioPlex
PWWP2A
Tdark
Novelty: 0.1712947
Score: 0.786
Data Source: STRINGDB
SARDH
Tbio
Family: Enzyme
Novelty: 0.02703115
Score: 0.65
Data Source: STRINGDB
TCF20
Tbio
Family: Epigenetic
Novelty: 0.00089239
Score: 0.604
Data Source: STRINGDB
PHF6
Tbio
Family: Epigenetic
Novelty: 0.00958984
Score: 0.594
Data Source: STRINGDB
Publication Statistics
PubMed Score  11.57

PubMed score by year
PubTator Score  4.4

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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