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Tbio
TMEM79
Transmembrane protein 79

Protein Summary
Description
Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295694
  • ENSP00000295694
  • ENSG00000163472
  • ENST00000405535
  • ENSP00000384748

Symbol
  • MATT
  • MATT
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
transcription factor binding site profile
0.78
cellular component
0.63
tissue sample
0.62
transcription factor
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.73   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 78   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.73   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 78   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
1
1
1
83.2
hemoglobin measurement
1
1
1
34.8
mean corpuscular hemoglobin concentration
1
1
1
34.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
1
83.2
hemoglobin measurement
1
34.8
mean corpuscular hemoglobin concentration
1
34.8
Gene Ontology Terms (11)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
IntAct
Protein-Protein Interactions (23)
1 – 10 of 23
FLOT2
Tbio
Novelty: 0.00727325
p_int: 0.999999991
p_ni: 9e-9
Score: 0.359
Data Source: BioPlex,STRINGDB
GCNT2
Tbio
Family: Enzyme
Novelty: 0.03945461
p_int: 0.999981895
p_ni: 2.12e-7
p_wrong: 0.000017893
Score: 0.261
Data Source: BioPlex,STRINGDB
NAA35
Tbio
Family: Enzyme
Novelty: 0.04980045
Score: 0.698
Data Source: STRINGDB
SLC45A3
Tbio
Family: Transporter
Novelty: 0.0178929
Score: 0.647
Data Source: STRINGDB
CCDC22
Tbio
Novelty: 0.01400901
Score: 0.643
Data Source: STRINGDB
MSR1
Tbio
Novelty: 0.0037302
Score: 0.619
Data Source: STRINGDB
SMG5
Tbio
Novelty: 0.04143189
Score: 0.612
Data Source: STRINGDB
C3orf58
Tbio
Novelty: 0.03694539
Score: 0.55
Data Source: STRINGDB
NUB1
Tbio
Novelty: 0.00736082
Score: 0.549
Data Source: STRINGDB
ASCC2
Tbio
Novelty: 0.12261896
Score: 0.543
Data Source: STRINGDB
Publication Statistics
PubMed Score  16.73

PubMed score by year
PubTator Score  4.66

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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