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Tdark
DCDC2C
Doublecortin domain-containing protein 2C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000399143
  • ENSP00000382097
  • ENSG00000214866
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.92
tissue
0.76
gene perturbation
0.62
disease
0.51
cell line
0.5


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.01   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 7   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.01   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 7   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolite measurement
1
1
1
33
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolite measurement
1
33
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A8MYV0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (11)
1 – 10 of 11
DCLK3
Tchem
Family: Kinase
Novelty: 0.00454456
Score: 0.623
Data Source: STRINGDB
TCERG1L
Tbio
Novelty: 0.24337643
Score: 0.558
Data Source: STRINGDB
FRMD4B
Tbio
Novelty: 0.20691438
Score: 0.558
Data Source: STRINGDB
GAK
Tchem
Family: Kinase
Novelty: 0.00731928
Score: 0.483
Data Source: STRINGDB
ZSCAN4
Tbio
Family: TF
Novelty: 0.03803132
Score: 0.474
Data Source: STRINGDB
EEFSEC
Tbio
Novelty: 0.00847753
Score: 0.473
Data Source: STRINGDB
CRIM1
Tbio
Novelty: 0.02742737
Score: 0.44
Data Source: STRINGDB
FAM110C
Tbio
Novelty: 0.42948302
Score: 0.426
Data Source: STRINGDB
EIPR1
Tbio
Novelty: 0.08803081
Score: 0.41
Data Source: STRINGDB
TRAPPC12
Tbio
Novelty: 0.09847363
Score: 0.408
Data Source: STRINGDB
Publication Statistics
PubMed Score  1.01

PubMed score by year
PubTator Score  0.63

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer