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Tbio
FOXI2
Forkhead box protein I2

Protein Summary
Description
Possible transcriptional activator.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000388920
  • ENSP00000373572
  • ENSG00000186766
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.56
biological process
0.46
PubMedID
0.42
chemical
0.41
histone modification site profile
0.41


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
forkhead box I2
VGNC:7227
466231
Mouse
MGI:3028075
270004
Rat
RGD:621739
246073
Dog
forkhead box I2
VGNC:40952
611594
Cow
forkhead box I2
VGNC:29088
613373
Species
Name
OMA
EggNOG
Inparanoid
Chimp
forkhead box I2
Mouse
Rat
Dog
forkhead box I2
Cow
forkhead box I2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6ZQN5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (37)
1 – 10 of 37
PAX8
Tbio
Family: TF
Novelty: 0.0014232
Score: 0.758
Data Source: STRINGDB
DLX3
Tbio
Family: TF
Novelty: 0.00887868
Score: 0.658
Data Source: STRINGDB
SOX5
Tbio
Family: TF
Novelty: 0.00623121
Score: 0.655
Data Source: STRINGDB
ZDHHC14
Tbio
Family: Enzyme
Novelty: 0.09974314
Score: 0.599
Data Source: STRINGDB
SOX11
Tbio
Family: TF
Novelty: 0.00516158
Score: 0.568
Data Source: STRINGDB
FGF3
Tbio
Novelty: 0.00474087
Score: 0.566
Data Source: STRINGDB
ZSCAN18
Tdark
Family: TF
Novelty: 0.38794947
Score: 0.561
Data Source: STRINGDB
ZNF471
Tdark
Family: TF
Novelty: 0.31061952
Score: 0.56
Data Source: STRINGDB
CLVS1
Tbio
Novelty: 0.275056
Score: 0.549
Data Source: STRINGDB
CCDC88C
Tbio
Novelty: 0.0495648
Score: 0.536
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.18

PubMed score by year
PubTator Score  1.06

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer