You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
FAM50B
Protein FAM50B

Protein Summary
Description
This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380272
  • ENSP00000369625
  • ENSG00000145945
  • ENST00000380274
  • ENSP00000369627
  • ENST00000648326
  • ENSP00000496837

Symbol
  • X5L
  • X5L
  • D6S2654E
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
histone modification site profile
0.76
disease perturbation
0.68
tissue sample
0.62
transcription factor binding site profile
0.59


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.64   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.64   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 50 member B
VGNC:11078
462405
Mouse
MGI:1351640
108161
Rat
RGD:1563458
306883
C. elegans
179970
Fruitfly
FBgn0039557
43347
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 50 member B
Mouse
Rat
C. elegans
Fruitfly
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9Y247-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Protein-Protein Interactions (29)
1 – 10 of 29
WBP4
Tbio
Novelty: 0.10095907
Score: 0.594
Data Source: STRINGDB
ZNF597
Tbio
Family: TF
Novelty: 0.04420398
Score: 0.563
Data Source: STRINGDB
NAP1L5
Tbio
Novelty: 0.10378595
Score: 0.545
Data Source: STRINGDB
ZDBF2
Tdark
Novelty: 0.19205154
Score: 0.53
Data Source: STRINGDB
HM13
Tbio
Family: Enzyme
Novelty: 0.0051333
Score: 0.523
Data Source: STRINGDB
NAA60
Tbio
Family: Enzyme
Novelty: 0.04868374
Score: 0.521
Data Source: STRINGDB
DIRAS3
Tbio
Family: Enzyme
Novelty: 0.01313162
Score: 0.498
Data Source: STRINGDB
SVOPL
Tdark
Novelty: 0.46448049
Score: 0.489
Data Source: STRINGDB
PLAGL1
Tbio
Family: TF
Novelty: 0.00845226
Score: 0.48
Data Source: STRINGDB
GNAS
Tbio
Novelty: 0.00284739
Score: 0.472
Data Source: STRINGDB
Publication Statistics
PubMed Score  7.64

PubMed score by year
PubTator Score  4.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer