Tbio CD83 CD83 antigen

Protein Summary

Description

May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation. The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Uniprot Accession IDs

• Q01151
• Q5THX9
• hCD83

Gene Name

• CD83

Ensembl ID

• ENST00000379153
• ENSP00000368450
• ENSG00000112149

Symbol

• BL11
• HB15

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
PubMedID	0.98
gene perturbation	0.95
virus perturbation	0.9
transcription factor binding site profile	0.79
disease	0.75

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 747.32   (req: < 5)

Gene RIFs: 68   (req: <= 3)

Antibodies: 863   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 747.32   (req: >= 5)

Gene RIFs: 68   (req: > 3)

Antibodies: 863   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0