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Tbio
NRSN1
Neurensin-1

Protein Summary
Description
May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. May play a role in memory consolidation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378478
  • ENSP00000367739
  • ENSG00000152954
  • ENST00000378491
  • ENSP00000367752

Symbol
  • VMP
  • VMP
  • p24
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.93
cellular component
0.67
microRNA
0.54
PubMedID
0.5
transcription factor binding site profile
0.49


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.85   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.85   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neurensin 1
VGNC:11134
750895
Macaque
neurensin 1
707362
Mouse
MGI:894662
22360
Rat
RGD:1307833
291129
Dog
neurensin 1
VGNC:43976
478734
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neurensin 1
Macaque
neurensin 1
Mouse
Rat
Dog
neurensin 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IZ57-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (31)
1 – 10 of 31
TLCD1
Tdark
Novelty: 0.76223034
Score: 0.726
Data Source: STRINGDB
KIAA0319
Tbio
Novelty: 0.01425914
Score: 0.648
Data Source: STRINGDB
THTPA
Tbio
Family: Enzyme
Novelty: 0.06922501
Score: 0.644
Data Source: STRINGDB
FAM166B
Tdark
Novelty: 3.58419283
Score: 0.637
Data Source: STRINGDB
DCDC2
Tbio
Novelty: 0.00395729
Score: 0.59
Data Source: STRINGDB
PLXNA3
Tbio
Novelty: 0.02016528
Score: 0.566
Data Source: STRINGDB
CNTFR
Tbio
Novelty: 0.0188716
Score: 0.56
Data Source: STRINGDB
ZBTB16
Tbio
Family: TF
Novelty: 0.0034205
Score: 0.557
Data Source: STRINGDB
GADD45B
Tbio
Novelty: 0.00611526
Score: 0.556
Data Source: STRINGDB
KAAG1
Tdark
Novelty: 0.97046572
Score: 0.553
Data Source: STRINGDB
Publication Statistics
PubMed Score  16.85

PubMed score by year
PubTator Score  92.74

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer