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Tbio
FAM120C
Constitutive coactivator of PPAR-gamma-like protein 2

Protein Summary
Description
This gene encodes a potential transmembrane protein and lies in a region where mutations and deletions have been associated with intellectual disability and autism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375180
  • ENSP00000364324
  • ENSG00000184083
  • ENST00000477084
  • ENSP00000420718

Symbol
  • CXorf17
  • ORF34
  • CXorf17
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.77
small molecule perturbation
0.69
cell type or tissue
0.62
tissue sample
0.6
virus perturbation
0.59


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.38   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.38   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 120C
VGNC:3767
473875
Macaque
family with sequence similarity 120C
700888
Mouse
MGI:2387687
207375
Opossum
family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]
Zebrafish
ZDB-GENE-090313-228
557842
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 120C
Macaque
family with sequence similarity 120C
Mouse
Opossum
family with sequence similarity 120C [Source:HGNC Symbol;Acc:HGNC:16949]
Zebrafish
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9NX05-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (27)
1 – 10 of 27
P4HA3
Tbio
Family: Enzyme
Novelty: 0.03832564
p_int: 0.999989761
p_ni: 0.000010236
p_wrong: 3e-9
Score: 0.237
Data Source: BioPlex,STRINGDB
WNK3
Tchem
Family: Kinase
Novelty: 0.03382701
Score: 0.767
Data Source: STRINGDB
DNAJC28
Tbio
Novelty: 0.02849281
Score: 0.731
Data Source: STRINGDB
PHF8
Tchem
Family: Epigenetic
Novelty: 0.01946151
Score: 0.72
Data Source: STRINGDB
MPLKIP
Tbio
Family: Enzyme
Novelty: 0.01661924
Score: 0.669
Data Source: STRINGDB
ERCC5
Tchem
Family: Enzyme
Novelty: 0.00819696
Score: 0.647
Data Source: STRINGDB
PRRT1
Tbio
Novelty: 0.08707857
Score: 0.63
Data Source: STRINGDB
TMEM59
Tbio
Novelty: 0.0329414
Score: 0.626
Data Source: STRINGDB
CTTNBP2
Tbio
Novelty: 0.00241
Score: 0.59
Data Source: STRINGDB
CWC15
Tbio
Novelty: 0.00205068
Score: 0.568
Data Source: STRINGDB
Publication Statistics
PubMed Score  33.38

PubMed score by year
PubTator Score  8.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer