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Tbio
PI16
Peptidase inhibitor 16

Protein Summary
Description
May inhibit cardiomyocyte growth.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373674
  • ENSP00000362778
  • ENSG00000164530
  • ENST00000611814
  • ENSP00000478888
  • ENST00000647861
  • ENSP00000497550

Symbol
  • CRISP9
  • PSPBP
  • CD364
  • PSPBP
  • CRISP9
  • MSMBBP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.6
cell line
0.59
biological process
0.58
transcription factor
0.58
gene perturbation
0.55


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.89   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 170   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.89   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 170   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peptidase inhibitor 16
VGNC:3618
471994
Macaque
peptidase inhibitor 16
719301
Mouse
MGI:1921366
74116
Rat
RGD:1304760
294312
Dog
peptidase inhibitor 16
VGNC:44515
481769
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peptidase inhibitor 16
Macaque
peptidase inhibitor 16
Mouse
Rat
Dog
peptidase inhibitor 16
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q6UXB8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (21)
1 – 10 of 21
LARGE2
Tbio
Family: Enzyme
Novelty: 0.11843777
Score: 0.755
Data Source: STRINGDB
ITIH3
Tbio
Novelty: 0.04201144
Score: 0.666
Data Source: STRINGDB
AP1AR
Tbio
Novelty: 0.01660994
Score: 0.635
Data Source: STRINGDB
SERPINB13
Tbio
Novelty: 0.01753451
Score: 0.634
Data Source: STRINGDB
NCOA4
Tbio
Novelty: 0.00487453
Score: 0.621
Data Source: STRINGDB
SERPINI2
Tbio
Novelty: 0.01926088
Score: 0.608
Data Source: STRINGDB
C7
Tbio
Novelty: 0.01540501
Score: 0.608
Data Source: STRINGDB
MSMB
Tbio
Novelty: 0.00241546
Score: 0.574
Data Source: STRINGDB
HLA-DRA
Tbio
Novelty: 0.0060214
Score: 0.524
Data Source: STRINGDB
EZH2
Tclin
Family: Epigenetic
Novelty: 0.00052816
Score: 0.508
Data Source: STRINGDB
Publication Statistics
PubMed Score  51.89

PubMed score by year
PubTator Score  6.66

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer