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Tbio
RSPH9
Radial spoke head protein 9 homolog

Protein Summary
Description
Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. This gene encodes a protein thought to be a component of the radial spoke head in motile cilia and flagella. Mutations in this gene are associated with primary ciliary dyskinesia 12. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372163
  • ENSP00000361236
  • ENSG00000172426
  • ENST00000372165
  • ENSP00000361238

Symbol
  • C6orf206
  • MRPS18AL1
  • CILD12
  • C6orf206
  • MRPS18AL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.59
tissue sample
0.56
cell line
0.52
transcription factor perturbation
0.47
virus perturbation
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.7   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.7   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (7)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
GO_Central
Inferred from Direct Assay (IDA)
GO_Central
Inferred by Curator (IC)
BHF-UCL
Protein-Protein Interactions (84)
1 – 10 of 84
ZC3H4
Tbio
Novelty: 0.14897433
p_int: 0.999975826
p_ni: 0.000018754
p_wrong: 0.00000542
Score: 0.527
Data Source: BioPlex,STRINGDB
LONP2
Tbio
Family: Enzyme
Novelty: 0.04499043
p_int: 0.999934988
p_ni: 0.000064421
p_wrong: 5.91e-7
Score: 0.21
Data Source: BioPlex,STRINGDB
BCR
Tclin
Novelty: 0.00127709
p_int: 0.998266831
p_ni: 0.001732867
p_wrong: 3.02e-7
Score: 0.167
Data Source: BioPlex,STRINGDB
PPP1R10
Tbio
Family: Enzyme
Novelty: 0.01119155
p_int: 0.996463022
p_ni: 0.003535104
p_wrong: 0.000001874
Score: 0.2
Data Source: BioPlex,STRINGDB
EIF3H
Tbio
Novelty: 0.02564681
p_int: 0.995725305
p_ni: 0.004274695
Score: 0.812
Data Source: BioPlex,STRINGDB
EIF3A
Tbio
Novelty: 0.00434615
p_int: 0.983007521
p_ni: 0.016992479
Score: 0.722
Data Source: BioPlex,STRINGDB
MOCS3
Tbio
Family: Enzyme
Novelty: 0.039209
p_int: 0.976816471
p_ni: 0.023183529
Score: 0.187
Data Source: BioPlex,STRINGDB
EIF3C
Tbio
Novelty: 0.02844331
p_int: 0.842545323
p_ni: 0.157454677
Score: 0.722
Data Source: BioPlex,STRINGDB
EIF3B
Tbio
Novelty: 0.00889042
p_int: 0.770790161
p_ni: 0.229209839
Score: 0.812
Data Source: BioPlex,STRINGDB
EIF3E
Tbio
Novelty: 0.02154456
p_int: 0.761313261
p_ni: 0.238686739
Score: 0.809
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  12.70

PubMed score by year
PubTator Score  5.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer