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Tdark
DMRTB1
Doublesex- and mab-3-related transcription factor B1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371445
  • ENSP00000360500
  • ENSG00000143006
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.81
molecular function
0.76
gene perturbation
0.62
cell line
0.56
biological process
0.43


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.27   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.27   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
beta-amyloid 1-42 measurement
1
1
1
3.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
beta-amyloid 1-42 measurement
1
3.2
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
DMRT like family B with proline rich C-terminal 1
VGNC:6779
738249
Mouse
MGI:1927125
56296
Rat
RGD:1560921
313484
Cow
DMRT like family B with proline rich C-terminal 1
VGNC:54419
516987
Pig
DMRT like family B with proline rich C-terminal 1
100515733
Species
Name
OMA
EggNOG
Inparanoid
Chimp
DMRT like family B with proline rich C-terminal 1
Mouse
Rat
Cow
DMRT like family B with proline rich C-terminal 1
Pig
DMRT like family B with proline rich C-terminal 1
Protein-Protein Interactions (29)
1 – 10 of 29
TRIM11
Tbio
Family: Enzyme
Novelty: 0.02243955
p_int: 0.995444904
p_ni: 0.004555094
p_wrong: 3e-9
Score: 0.189
Data Source: BioPlex,STRINGDB
KLHL15
Tbio
Novelty: 0.54712519
p_int: 0.916907981
p_ni: 0.083092019
Score: 0.205
Data Source: BioPlex,STRINGDB
TSACC
Tbio
Novelty: 0.62833606
Score: 0.543
Data Source: STRINGDB
RIMBP3C
Tdark
Novelty: 12.18975991
Score: 0.541
Data Source: STRINGDB
RIMBP3B
Tdark
Novelty: 0.78518303
Score: 0.521
Data Source: STRINGDB
C2CD6
Tdark
Novelty: 1.30543834
Score: 0.509
Data Source: STRINGDB
C22orf23
Tdark
Novelty: 0.11734709
Score: 0.501
Data Source: STRINGDB
LMCD1
Tbio
Novelty: 0.06810419
Score: 0.5
Data Source: STRINGDB
SLC25A51
Tdark
Family: Transporter
Novelty: 0.21568087
Score: 0.488
Data Source: STRINGDB
CFAP74
Tdark
Novelty: 0.37177561
Score: 0.483
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.27

PubMed score by year
PubTator Score  0.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer