You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
IFI44L
Interferon-induced protein 44-like

Protein Summary
Description
Exhibits a low antiviral activity against hepatitis C virus.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370751
  • ENSP00000359787
  • ENSG00000137959

Symbol
  • C1orf29
  • GS3686
  • C1orf29
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
1
virus perturbation
1
small molecule perturbation
0.69
tissue sample
0.67
cell type or tissue
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.03   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.03   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
MMR-related febrile seizures
1
1
0
1.4
62.1
Febrile seizure (within the age range of 3 months to 6 years)
1
1
0
1.4
47.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
MMR-related febrile seizures
0
1.4
62.1
Febrile seizure (within the age range of 3 months to 6 years)
0
1.4
47.6
Pathways (134)
Items per page:
1 – 5 of 134
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Non-genomic actions of 1,25 dihydroxyvitamin D3
WikiPathways
Non-genomic actions of 1,25 dihydroxyvitamin D3
WikiPathways
Non-genomic actions of 1,25 dihydroxyvitamin D3
WikiPathways
Non-genomic actions of 1,25 dihydroxyvitamin D3
WikiPathways
Non-genomic actions of 1,25 dihydroxyvitamin D3
Name
Explore in Pharos
Explore in Source
Non-genomic actions of 1,25 dihydroxyvitamin D3
Non-genomic actions of 1,25 dihydroxyvitamin D3
Non-genomic actions of 1,25 dihydroxyvitamin D3
Non-genomic actions of 1,25 dihydroxyvitamin D3
Non-genomic actions of 1,25 dihydroxyvitamin D3
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (67)
1 – 10 of 67
IFNA21
Tbio
Novelty: 0.00581034
p_int: 0.999939494
p_ni: 3.53e-7
p_wrong: 0.000060153
Score: 0.337
Data Source: BioPlex,STRINGDB
IFIT1
Tbio
Novelty: 0.00562299
Score: 0.957
Data Source: STRINGDB
RSAD2
Tbio
Novelty: 0.0056473
Score: 0.952
Data Source: STRINGDB
IFIT3
Tbio
Novelty: 0.00568113
Score: 0.95
Data Source: STRINGDB
MX1
Tbio
Novelty: 0.00072554
Score: 0.948
Data Source: STRINGDB
IFI6
Tbio
Novelty: 0.02590679
Score: 0.948
Data Source: STRINGDB
ISG15
Tbio
Novelty: 0.00203781
Score: 0.935
Data Source: STRINGDB
OAS1
Tbio
Family: Enzyme
Novelty: 0.00532331
Score: 0.931
Data Source: STRINGDB
OAS3
Tbio
Family: Enzyme
Novelty: 0.02422229
Score: 0.928
Data Source: STRINGDB
OAS2
Tbio
Family: Enzyme
Novelty: 0.01673393
Score: 0.928
Data Source: STRINGDB
Publication Statistics
PubMed Score  30.03

PubMed score by year
PubTator Score  14.7

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer