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Tdark
SUCO
SUN domain-containing ossification factor

Protein Classes
Protein Summary
Description
Required for bone modeling during late embryogenesis. Regulates type I collagen synthesis in osteoblasts during their postnatal maturation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000263688
  • ENSP00000263688
  • ENSG00000094975
  • ENST00000367723
  • ENSP00000356696
  • ENST00000608151
  • ENSP00000477484

Symbol
  • C1orf9
  • CH1
  • OPT
  • SLP1
  • CH1
  • OPT
  • SLP1
  • C1orf9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
phenotype
0.93
histone modification site profile
0.8
transcription factor binding site profile
0.75
microRNA
0.67
cellular component
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1306.6   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 5   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1306.6   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (11)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (49)
1 – 10 of 49
KCNS3
Tclin
Family: IC
Novelty: 0.05882087
p_int: 0.999999092
p_ni: 9.08e-7
Score: 0.167
Data Source: BioPlex,STRINGDB
TRAPPC1
Tbio
Novelty: 0.09781468
p_int: 0.999997993
p_ni: 0.000002007
Score: 0.189
Data Source: BioPlex,STRINGDB
DNASE2B
Tbio
Family: Enzyme
Novelty: 0.02506932
p_int: 0.999996059
p_ni: 0.000003941
Score: 0.189
Data Source: BioPlex,STRINGDB
P4HB
Tbio
Family: Enzyme
Novelty: 0.00107905
p_int: 0.999771614
p_ni: 0.000228367
p_wrong: 1.9e-8
Score: 0.558
Data Source: BioPlex,STRINGDB
TAPT1
Tbio
Novelty: 0.12057711
Score: 0.763
Data Source: STRINGDB
PIGC
Tbio
Family: Enzyme
Novelty: 0.02057578
Score: 0.727
Data Source: STRINGDB
PRRC2C
Tbio
Novelty: 0.25128003
Score: 0.718
Data Source: STRINGDB
PLPP6
Tbio
Family: Enzyme
Novelty: 0.10221642
Score: 0.71
Data Source: STRINGDB
TMED5
Tdark
Novelty: 0.32104091
Score: 0.709
Data Source: STRINGDB
VPS33A
Tbio
Novelty: 0.08316241
Score: 0.706
Data Source: STRINGDB
Publication Statistics
PubMed Score  1306.60

PubMed score by year
PubTator Score  299.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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