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Tdark
KIAA1614
Uncharacterized protein KIAA1614

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000367587
  • ENSP00000356559
  • ENSG00000135835
  • ENST00000367588
  • ENSP00000356560
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.62
histone modification site profile
0.53
cellular component
0.52
cell line
0.51
cell type or tissue
0.51


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.35   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 28   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.35   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 28   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
1
1
74.3
myeloid white cell count
1
1
1
64.5
heel bone mineral density
2
1
2
64.2
glomerular filtration rate
3
1
2
7.2
47.4
leukocyte count
1
1
1
25.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
74.3
myeloid white cell count
1
64.5
heel bone mineral density
2
64.2
glomerular filtration rate
2
7.2
47.4
leukocyte count
1
25.4
Protein-Protein Interactions (28)
1 – 10 of 28
PRKCZ
Tchem
Family: Kinase
Novelty: 0.00201366
Score: 0.752
Data Source: STRINGDB
PRKCI
Tchem
Family: Kinase
Novelty: 0.0076377
Score: 0.752
Data Source: STRINGDB
KIAA2012
Tdark
Novelty: 21
Score: 0.652
Data Source: STRINGDB
TPBGL
Tdark
Novelty: 0.89192563
Score: 0.642
Data Source: STRINGDB
RBBP8NL
Tdark
Novelty: 3.33075673
Score: 0.578
Data Source: STRINGDB
FAM217B
Tdark
Novelty: 4.03122155
Score: 0.569
Data Source: STRINGDB
FAM186A
Tdark
Novelty: 2.29255942
Score: 0.553
Data Source: STRINGDB
C21orf58
Tdark
Novelty: 1.16236162
Score: 0.552
Data Source: STRINGDB
EXOC3L4
Tdark
Novelty: 0.65394237
Score: 0.533
Data Source: STRINGDB
EFCAB5
Tdark
Novelty: 0.62310294
Score: 0.529
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.35

PubMed score by year
PubTator Score  0.85

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer