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Tdark
PRRC2B
Protein PRRC2B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000357304
  • ENSP00000349856
  • ENSG00000130723
  • ENST00000405995
  • ENSP00000384606
  • ENST00000458550
  • ENSP00000398853

Symbol
  • BAT2L
  • BAT2L1
  • KIAA0515
  • BAT2L
  • BAT2L1
  • LQFBS-1
  • KIAA0515
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.98
cellular component
0.9
disease perturbation
0.9
kinase perturbation
0.84
microRNA
0.82


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 30   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.55   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 30   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
2
1
2
83.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
2
83.4
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
proline rich coiled-coil 2B
VGNC:9216
464810
Mouse
MGI:1923304
227723
Rat
RGD:1595906
296637
Dog
proline rich coiled-coil 2B
VGNC:45053
491288
Cow
proline rich coiled-coil 2B
VGNC:33405
505073
Species
Name
OMA
EggNOG
Inparanoid
Chimp
proline rich coiled-coil 2B
Mouse
Rat
Dog
proline rich coiled-coil 2B
Cow
proline rich coiled-coil 2B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5JSZ5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (50)
1 – 10 of 50
EIF3I
Tbio
Novelty: 0.04398155
p_int: 0.99999989
p_ni: 1.1e-7
Score: 0.682
Data Source: BioPlex,STRINGDB
EIF3H
Tbio
Novelty: 0.02564681
p_int: 0.999996705
p_ni: 0.000003294
p_wrong: 1e-9
Score: 0.817
Data Source: BioPlex,STRINGDB
PLOD3
Tbio
Family: Enzyme
Novelty: 0.02211629
p_int: 0.999992098
p_ni: 0.000007902
Data Source: BioPlex
EIF3D
Tbio
Novelty: 0.0360717
p_int: 0.99999197
p_ni: 0.00000803
Data Source: BioPlex
EIF3L
Tbio
Novelty: 0.11054104
p_int: 0.999990737
p_ni: 0.000009263
Score: 0.811
Data Source: BioPlex,STRINGDB
EIF3F
Tbio
Novelty: 0.0319772
p_int: 0.999532785
p_ni: 0.000467196
p_wrong: 1.9e-8
Score: 0.679
Data Source: BioPlex,STRINGDB
JPH4
Tbio
Novelty: 0.07699598
p_int: 0.999489597
p_ni: 0.000510396
p_wrong: 7e-9
Data Source: BioPlex
PLOD1
Tbio
Family: Enzyme
Novelty: 0.00905345
p_int: 0.998459777
p_ni: 0.001540223
Data Source: BioPlex
NAGK
Tbio
Family: Kinase
Novelty: 0.01603908
p_int: 0.99117668
p_ni: 0.00882332
Data Source: BioPlex
CLEC11A
Tbio
Novelty: 0.03060601
p_int: 0.929611968
p_ni: 0.070388032
Data Source: BioPlex
Publication Statistics
PubMed Score  2.55

PubMed score by year
PubTator Score  1.39

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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