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Tbio
CCDC151
Coiled-coil domain-containing protein 151

Protein Summary
Description
Ciliary protein involved in outer dynein arm assembly and required for motile cilia function. This gene encodes a protein containing coiled-coil domains. The encoded protein functions in outer dynein arm assembly and is required for motile cilia function. Mutations in this gene result in primary ciliary dyskinesia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000356392
  • ENSP00000348757
  • ENSG00000198003

Symbol
  • CILD30
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.65
cell type or tissue
0.64
tissue sample
0.64
histone modification site profile
0.57
transcription factor
0.5


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.02   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.02   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (8)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Protein-Protein Interactions (62)
1 – 10 of 62
ALKBH2
Tbio
Family: Enzyme
Novelty: 0.02318716
p_int: 0.999998692
p_ni: 3.3e-8
p_wrong: 0.000001274
Score: 0.188
Data Source: BioPlex,STRINGDB
TRIM44
Tbio
Novelty: 0.00483553
p_int: 0.999892866
p_ni: 0.000107134
Data Source: BioPlex
IFT88
Tbio
Novelty: 0.00727114
p_int: 0.999765113
p_ni: 0.000233816
p_wrong: 0.000001071
Score: 0.299
Data Source: BioPlex,STRINGDB
CENPH
Tbio
Novelty: 0.02845079
p_int: 0.994504561
p_ni: 0.005495397
p_wrong: 4.2e-8
Data Source: BioPlex
IFT46
Tdark
Novelty: 0.11310911
p_int: 0.992087259
p_ni: 0.002399187
p_wrong: 0.005513554
Score: 0.824
Data Source: BioPlex,STRINGDB
IFT22
Tbio
Family: Enzyme
Novelty: 0.18342877
p_int: 0.990046524
p_ni: 0.009953407
p_wrong: 7e-8
Score: 0.667
Data Source: BioPlex,STRINGDB
IFT74
Tbio
Novelty: 0.07195266
p_int: 0.985393578
p_ni: 0.014606421
p_wrong: 1e-9
Score: 0.715
Data Source: BioPlex,STRINGDB
NSMCE4A
Tdark
Novelty: 0.45550673
p_int: 0.983578316
p_ni: 0.013865862
p_wrong: 0.002555822
Data Source: BioPlex
CCDC22
Tbio
Novelty: 0.01400901
p_int: 0.979062061
p_ni: 0.020937939
Score: 0.594
Data Source: BioPlex,STRINGDB
COMMD8
Tdark
Novelty: 0.33240242
p_int: 0.975835209
p_ni: 0.022626105
p_wrong: 0.001538686
Score: 0.85
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  7.02

PubMed score by year
PubTator Score  2.75

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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