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Tbio
VANGL1
Vang-like protein 1

Protein Summary
Description
This gene encodes a member of the tretraspanin family. The encoded protein may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310260
  • ENSP00000310800
  • ENSG00000173218
  • ENST00000355485
  • ENSP00000347672
  • ENST00000369509
  • ENSP00000358522
  • ENST00000369510
  • ENSP00000358523

Symbol
  • STB2
  • LPP2
  • STB2
  • STBM2
  • KITENIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.92
transcription factor binding site profile
0.81
PubMedID
0.73
virus perturbation
0.72
kinase perturbation
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 73.53   (req: < 5)
Gene RIFs: 28   (req: <= 3)
Antibodies: 167   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 73.53   (req: >= 5)
Gene RIFs: 28   (req: > 3)
Antibodies: 167   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (125)
1 – 10 of 125
GPR156
Tdark
Family: GPCR
Novelty: 0.46666667
p_int: 0.99999072
p_ni: 0.00000928
Data Source: BioPlex
HDGFL2
Tbio
Family: Epigenetic
Novelty: 0.12835229
p_int: 0.999986677
p_ni: 0.000013323
Data Source: BioPlex
ANKRD36B
Tdark
Novelty: 10
p_int: 0.999856775
p_ni: 0.000143225
Data Source: BioPlex
EPB41L1
Tbio
Novelty: 0.01521218
p_int: 0.999695322
p_ni: 0.000304678
Data Source: BioPlex
DVL2
Tbio
Novelty: 0.01142063
p_int: 0.999615176
p_ni: 0.000384824
Score: 0.977
Data Source: BioPlex,STRINGDB
CD44
Tbio
Novelty: 0.00013754
p_int: 0.999087781
p_ni: 0.000912219
Score: 0.209
Data Source: BioPlex,STRINGDB
DVL3
Tbio
Novelty: 0.02234457
p_int: 0.998701056
p_ni: 0.001298944
Score: 0.977
Data Source: BioPlex,STRINGDB
SDC2
Tbio
Novelty: 0.00780417
p_int: 0.99861114
p_ni: 0.00138886
Data Source: BioPlex
EPB41L3
Tbio
Novelty: 0.00828944
p_int: 0.997150325
p_ni: 0.002849675
Data Source: BioPlex
PNN
Tbio
Novelty: 0.00945912
p_int: 0.996958394
p_ni: 0.003041606
Data Source: BioPlex
Publication Statistics
PubMed Score  73.53

PubMed score by year
PubTator Score  39.97

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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