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Tbio
ZC3H7B
Zinc finger CCCH domain-containing protein 7B

Protein Classes
Protein Summary
Description
May be a specific regulator of miRNA biogenesis. Binds to microRNAs MIR7-1, MIR16-2 and MIR29A hairpins recognizing the 'ATA(A/T)' motif in the apical loop. This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts with the rotavirus non-structural protein NSP3. [provided by RefSeq, Jul 2008]
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
microRNA
0.77
tissue sample
0.75
protein domain
0.73
transcription factor binding site profile
0.66


Related Tools
GENEVA
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GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.66   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 101   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.66   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 101   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1328310
20286
Rat
RGD:1307064
315158
Horse
zinc finger CCCH-type containing 7B
VGNC:25170
100070641
Cow
zinc finger CCCH-type containing 7B
VGNC:37109
534109
Anole lizard
zinc finger CCCH-type containing 7B
100557365
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
zinc finger CCCH-type containing 7B
Cow
zinc finger CCCH-type containing 7B
Anole lizard
zinc finger CCCH-type containing 7B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9UGR2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (21)
1 – 10 of 21
MBTD1
Tbio
Family: Epigenetic
Novelty: 0.11651052
Score: 0.724
Data Source: STRINGDB
EIF4G1
Tbio
Novelty: 0.00170995
Score: 0.701
Data Source: STRINGDB
MEAF6
Tbio
Novelty: 0.0914094
Score: 0.684
Data Source: STRINGDB
CXorf67
Tdark
Novelty: 0.19833947
Score: 0.678
Data Source: STRINGDB
BCOR
Tbio
Novelty: 0.05718292
Score: 0.63
Data Source: STRINGDB
SH2D3C
Tbio
Novelty: 0.00356605
Score: 0.581
Data Source: STRINGDB
NUTM2A
Tdark
Novelty: 0.16557531
Score: 0.553
Data Source: STRINGDB
JAZF1
Tbio
Novelty: 0.01639328
Score: 0.538
Data Source: STRINGDB
PHF1
Tbio
Family: Epigenetic
Novelty: 0.00430297
Score: 0.521
Data Source: STRINGDB
CCNB3
Tbio
Novelty: 0.01885821
Score: 0.513
Data Source: STRINGDB
Publication Statistics
PubMed Score  9.66

PubMed score by year
PubTator Score  3.89

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer