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Tbio
TSPAN18
Tetraspanin-18

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 57   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.37   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 57   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
81
intraocular pressure measurement
1
1
1
25.9
brain measurement
1
1
0
274.1
6.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
81
intraocular pressure measurement
1
25.9
brain measurement
0
274.1
6.7
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (19)
1 – 10 of 19
FITM2
Tdark
Novelty: 0.01882177
p_int: 0.862410462
p_ni: 0.073356583
p_wrong: 0.064232955
Score: 0.303
Data Source: BioPlex,STRINGDB
GHITM
Tbio
Novelty: 0.00360652
Score: 0.651
Data Source: STRINGDB
PICK1
Tbio
Novelty: 0.0058265
Score: 0.608
Data Source: STRINGDB
TSPAN32
Tbio
Novelty: 0.08323845
Score: 0.591
Data Source: STRINGDB
NKAPL
Tbio
Novelty: 0.24172313
Score: 0.589
Data Source: STRINGDB
ZSCAN31
Tdark
Family: TF
Novelty: 0.24834253
Score: 0.556
Data Source: STRINGDB
ZKSCAN4
Tbio
Family: TF
Novelty: 0.33154485
Score: 0.537
Data Source: STRINGDB
RNF130
Tdark
Family: Enzyme
Novelty: 0.26931521
Score: 0.527
Data Source: STRINGDB
TSPAN19
Tdark
Novelty: 0.92458543
Score: 0.476
Data Source: STRINGDB
CD300LG
Tbio
Novelty: 0.12664188
Score: 0.461
Data Source: STRINGDB
Publication Statistics
PubMed Score  14.37

PubMed score by year
PubTator Score  6.55

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer