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Tbio
SLC35D3
Solute carrier family 35 member D3

Protein Summary
Description
May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331858
  • ENSP00000333591
  • ENSG00000182747

Symbol
  • FRCL1
  • FRCL1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.86
histone modification site profile
0.8
PubMedID
0.61
microRNA
0.53
cell line
0.48


Related Tools
RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.15   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.15   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member D3
VGNC:11289
463025
Mouse
MGI:1923407
76157
Rat
RGD:1309428
308717
Dog
solute carrier family 35 member D3
VGNC:46372
100856033
Cow
solute carrier family 35 member D3
VGNC:34829
539925
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 35 member D3
Mouse
Rat
Dog
solute carrier family 35 member D3
Cow
solute carrier family 35 member D3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q5M8T2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (27)
1 – 10 of 27
GPCPD1
Tdark
Family: Enzyme
Novelty: 0.03548168
p_int: 1
Score: 0.692
Data Source: BioPlex,STRINGDB
ATP6V0A1
Tbio
Family: Enzyme
Novelty: 0.02009317
p_int: 0.858124869
p_ni: 0.141875131
Score: 0.187
Data Source: BioPlex,STRINGDB
RAB27A
Tchem
Family: Enzyme
Novelty: 0.00369416
Score: 0.756
Data Source: STRINGDB
SLC35A5
Tdark
Family: Transporter
Novelty: 0.89836104
Score: 0.649
Data Source: STRINGDB
SLC35C2
Tdark
Family: Transporter
Novelty: 0.27116526
Score: 0.645
Data Source: STRINGDB
IL22RA2
Tbio
Novelty: 0.03455127
Score: 0.64
Data Source: STRINGDB
SLC35A3
Tbio
Family: Transporter
Novelty: 0.02472244
Score: 0.629
Data Source: STRINGDB
SLC35B3
Tdark
Family: Transporter
Novelty: 0.10252233
Score: 0.62
Data Source: STRINGDB
OLIG3
Tbio
Family: TF
Novelty: 0.06568103
Score: 0.609
Data Source: STRINGDB
SLC35A4
Tdark
Family: Transporter
Novelty: 0.6182609
Score: 0.595
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.15

PubMed score by year
PubTator Score  1.48

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer