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Tdark
EFCAB13
EF-hand calcium-binding domain-containing protein 13

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331493
  • ENSP00000332111
  • ENSG00000178852
  • ENST00000517484
  • ENSP00000430048

Symbol
  • C17orf57
  • C17orf57
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.76
histone modification site profile
0.75
PubMedID
0.71
tissue sample
0.69
tissue
0.57


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.89   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 89   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.89   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 89   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
2
1
3
85.8
total cholesterol measurement
2
1
3
84.7
mathematical ability
1
1
1
77.9
membrane-bound aminopeptidase P measurement
1
1
1
56.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
low density lipoprotein cholesterol measurement
3
85.8
total cholesterol measurement
3
84.7
mathematical ability
1
77.9
membrane-bound aminopeptidase P measurement
1
56.3
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 13
VGNC:12097
468295
Macaque
EF-hand calcium binding domain 13
716404
Mouse
MGI:3651790
105242472
Horse
EF-hand calcium binding domain 13 [Source:HGNC Symbol;Acc:HGNC:26864]
Pig
EF-hand calcium-binding domain-containing protein 13-like
100624995
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 13
Macaque
EF-hand calcium binding domain 13
Mouse
Horse
EF-hand calcium binding domain 13 [Source:HGNC Symbol;Acc:HGNC:26864]
Pig
EF-hand calcium-binding domain-containing protein 13-like
Protein-Protein Interactions (35)
1 – 10 of 35
ACSBG2
Tbio
Family: Enzyme
Novelty: 0.1072938
Score: 0.737
Data Source: STRINGDB
MYH10
Tbio
Novelty: 0.00624251
Score: 0.634
Data Source: STRINGDB
FAM187B
Tdark
Novelty: 0.59092623
Score: 0.617
Data Source: STRINGDB
OBSCN
Tbio
Family: Kinase
Novelty: 0.01173699
Score: 0.601
Data Source: STRINGDB
SPEG
Tbio
Family: Kinase
Novelty: 0.01666376
Score: 0.601
Data Source: STRINGDB
EFCAB3
Tdark
Novelty: 0.7941269
Score: 0.601
Data Source: STRINGDB
ZNF80
Tdark
Family: TF
Novelty: 0.03198898
Score: 0.589
Data Source: STRINGDB
SPERT
Tbio
Novelty: 0.12255061
Score: 0.585
Data Source: STRINGDB
OR7G3
Tdark
Family: oGPCR
Novelty: 1.25607075
Score: 0.565
Data Source: STRINGDB
ZNF599
Tdark
Family: TF
Novelty: 1.49090633
Score: 0.555
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.89

PubMed score by year
PubTator Score  0.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer