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Tdark
ZNF354B
Zinc finger protein 354B

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000322434
  • ENSP00000327143
  • ENSG00000178338

Symbol
  • KID2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.76
virus perturbation
0.72
histone modification site profile
0.64
cell type or tissue
0.58
protein domain
0.58


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.28   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 13   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.28   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 13   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 354B
VGNC:4234
471765
Macaque
zinc finger protein 354B
712885
Mouse
MGI:1351476
27274
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 354B
Macaque
zinc finger protein 354B
Mouse
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96LW1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (15)
1 – 10 of 15
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.916
Data Source: STRINGDB
THG1L
Tbio
Family: Enzyme
Novelty: 0.17339179
Score: 0.473
Data Source: STRINGDB
WDR55
Tdark
Novelty: 0.51900003
Score: 0.464
Data Source: STRINGDB
SIMC1
Tbio
Novelty: 0.39770049
Score: 0.442
Data Source: STRINGDB
CYSTM1
Tdark
Novelty: 1.37759108
Score: 0.441
Data Source: STRINGDB
MFSD2A
Tbio
Novelty: 0.01709114
Score: 0.439
Data Source: STRINGDB
UHMK1
Tbio
Family: Kinase
Novelty: 0.04117277
Score: 0.437
Data Source: STRINGDB
HIGD2A
Tbio
Novelty: 0.21688773
Score: 0.43
Data Source: STRINGDB
RNF145
Tbio
Novelty: 0.30480192
Score: 0.425
Data Source: STRINGDB
PCYOX1L
Tdark
Family: Enzyme
Novelty: 1.25398886
Score: 0.42
Data Source: STRINGDB
Publication Statistics
PubMed Score  11.28

PubMed score by year
PubTator Score  3.7

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer