You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RNF166
RING finger protein 166

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312838
  • ENSP00000326095
  • ENSG00000158717
  • ENST00000537718
  • ENSP00000446301
  • ENST00000541206
  • ENSP00000440454
  • ENST00000567844
  • ENSP00000457336
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.81
disease perturbation
0.74
protein domain
0.73
transcription factor binding site profile
0.73
transcription factor
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 111   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.53   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 111   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
1
1
1
85.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
suntan
1
85.8
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (49)
1 – 10 of 49
LIG1
Tchem
Family: Enzyme
Novelty: 0.00326816
p_int: 0.999998636
p_ni: 0.000001297
p_wrong: 6.7e-8
Score: 0.34
Data Source: BioPlex,STRINGDB
TNKS2
Tchem
Family: Enzyme
Novelty: 0.00938509
p_int: 0.999997572
p_ni: 0.000002428
Data Source: BioPlex
TNKS
Tchem
Family: Enzyme
Novelty: 0.00404545
p_int: 0.999990241
p_ni: 0.000009759
Data Source: BioPlex
TNFAIP6
Tbio
Novelty: 0.0046811
p_int: 0.999921137
p_ni: 0.000039366
p_wrong: 0.000039497
Data Source: BioPlex
PARP11
Tbio
Family: Enzyme
Novelty: 0.11901686
p_int: 0.999890182
p_ni: 0.000107041
p_wrong: 0.000002777
Score: 0.787
Data Source: BioPlex,STRINGDB
MPDZ
Tbio
Novelty: 0.01656439
p_int: 0.999769557
p_ni: 0.000230443
Score: 0.189
Data Source: BioPlex,STRINGDB
PARP12
Tbio
Family: Enzyme
Novelty: 0.08076657
p_int: 0.999684542
p_ni: 0.00022912
p_wrong: 0.000086338
Score: 0.538
Data Source: BioPlex,STRINGDB
NF2
Tbio
Novelty: 0.00055092
p_int: 0.999555445
p_ni: 0.000444555
Score: 0.343
Data Source: BioPlex,STRINGDB
TNFAIP3
Tbio
Novelty: 0.00257088
p_int: 0.999545963
p_ni: 0.000304585
p_wrong: 0.000149452
Score: 0.173
Data Source: BioPlex,STRINGDB
KIF1A
Tbio
Novelty: 0.00505209
p_int: 0.999343176
p_ni: 0.000656796
p_wrong: 2.8e-8
Score: 0.173
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  2.53

PubMed score by year
PubTator Score  0.64

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer