You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
PSD3
PH and SEC7 domain-containing protein 3

Protein Summary
Description
Guanine nucleotide exchange factor for ARF6.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000286485
  • ENSP00000286485
  • ENSG00000156011
  • ENST00000327040
  • ENSP00000324127
  • ENST00000440756
  • ENSP00000401704

Symbol
  • EFA6D
  • EFA6R
  • HCA67
  • KIAA0942
  • EFA6D
  • EFA6R
  • HCA67
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.93
virus perturbation
0.92
PubMedID
0.79
microRNA
0.75
phenotype
0.72


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.81   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 148   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 23.81   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 148   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
0
1.1
70.6
lymphocyte count
1
1
1
54.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
70.6
lymphocyte count
1
54.1
Gene Ontology Terms (6)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (17)
1 – 10 of 17
ARF6
Tbio
Family: Enzyme
Novelty: 0.00278138
Score: 0.734
Data Source: STRINGDB
KCTD4
Tdark
Novelty: 2.1757288
Score: 0.682
Data Source: STRINGDB
SERPINI1
Tbio
Novelty: 0.00518205
Score: 0.542
Data Source: STRINGDB
PNRC2
Tbio
Novelty: 0.08731548
Score: 0.509
Data Source: STRINGDB
ZNF844
Tdark
Family: TF
Novelty: 12.1910828
Score: 0.497
Data Source: STRINGDB
IL1RAPL2
Tbio
Novelty: 0.13104919
Score: 0.486
Data Source: STRINGDB
CHP2
Tbio
Novelty: 0.15598265
Score: 0.447
Data Source: STRINGDB
SCHIP1
Tbio
Novelty: 0.0765945
Score: 0.445
Data Source: STRINGDB
CFAP77
Tdark
Novelty: 4.08287895
Score: 0.441
Data Source: STRINGDB
SCML1
Tdark
Novelty: 0.60106322
Score: 0.42
Data Source: STRINGDB
Publication Statistics
PubMed Score  23.81

PubMed score by year
PubTator Score  14.56

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer