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Tbio
PLXDC1
Plexin domain-containing protein 1

Protein Summary
Description
Plays a critical role in endothelial cell capillary morphogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315392
  • ENSP00000323927
  • ENSG00000161381
  • ENST00000578390
  • ENSP00000462089

Symbol
  • TEM3
  • TEM7
  • TEM3
  • TEM7
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.75
PubMedID
0.74
microRNA
0.7
cell line
0.62
gene perturbation
0.59


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 98.2   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 329   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 98.2   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 329   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (12)
Items per page:
10
1 – 10 of 10
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Non-traceable Author Statement (NAS)
UniProtKB
Non-traceable Author Statement (NAS)
UniProtKB
Non-traceable Author Statement (NAS)
UniProtKB
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (26)
1 – 10 of 26
CD248
Tbio
Novelty: 0.00063383
Score: 0.848
Data Source: STRINGDB
RASD2
Tbio
Family: Enzyme
Novelty: 0.00490468
Score: 0.792
Data Source: STRINGDB
NRF1
Tbio
Family: TF
Novelty: 0.00543248
Score: 0.723
Data Source: STRINGDB
ARHGEF17
Tbio
Novelty: 0.03360149
Score: 0.71
Data Source: STRINGDB
ADGRA2
Tbio
Family: GPCR
Novelty: 0.02854335
Score: 0.709
Data Source: STRINGDB
TNS3
Tbio
Novelty: 0.01631198
Score: 0.705
Data Source: STRINGDB
NID1
Tbio
Novelty: 0.00169075
Score: 0.611
Data Source: STRINGDB
ANTXR1
Tbio
Novelty: 0.00508081
Score: 0.589
Data Source: STRINGDB
TRARG1
Tbio
Novelty: 0.07729433
Score: 0.549
Data Source: STRINGDB
PADI4
Tchem
Family: Enzyme
Novelty: 0.0024252
Score: 0.549
Data Source: STRINGDB
Publication Statistics
PubMed Score  98.20

PubMed score by year
PubTator Score  19.48

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer