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Tbio
DCBLD2
Discoidin, CUB and LCCL domain-containing protein 2

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.53   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 221   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.53   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 221   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
discoidin, CUB and LCCL domain containing 2
VGNC:7055
460548
Macaque
discoidin, CUB and LCCL domain containing 2
700151
Mouse
MGI:1920629
73379
Rat
RGD:620543
155696
Dog
discoidin, CUB and LCCL domain containing 2
VGNC:39798
487949
Species
Name
OMA
EggNOG
Inparanoid
Chimp
discoidin, CUB and LCCL domain containing 2
Macaque
discoidin, CUB and LCCL domain containing 2
Mouse
Rat
Dog
discoidin, CUB and LCCL domain containing 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96PD2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (40)
1 – 10 of 40
PCDHB11
Tdark
Novelty: 0.80480462
p_int: 0.998962054
p_ni: 0.001037926
p_wrong: 2e-8
Data Source: BioPlex
FAM19A5
Tdark
Novelty: 0.07792418
p_int: 0.998709648
p_ni: 0.001290237
p_wrong: 1.14e-7
Data Source: BioPlex
TCTN2
Tbio
Novelty: 0.11617528
p_int: 0.996787174
p_ni: 0.003212229
p_wrong: 5.97e-7
Score: 0.195
Data Source: BioPlex,STRINGDB
HLA-DRA
Tbio
Novelty: 0.0060214
p_int: 0.995829319
p_ni: 0.00416913
p_wrong: 0.00000155
Score: 0.54
Data Source: BioPlex,STRINGDB
TMPRSS11B
Tdark
Family: Enzyme
Novelty: 1.20690443
p_int: 0.995643089
p_ni: 0.004356724
p_wrong: 1.86e-7
Data Source: BioPlex
SIAE
Tbio
Family: Enzyme
Novelty: 0.01138067
p_int: 0.991698582
p_ni: 0.007550401
p_wrong: 0.000751017
Score: 0.545
Data Source: BioPlex,STRINGDB
PTPRK
Tbio
Family: Enzyme
Novelty: 0.03149943
p_int: 0.98790686
p_ni: 0.009914801
p_wrong: 0.002178339
Score: 0.259
Data Source: BioPlex,STRINGDB
ITM2B
Tbio
Novelty: 0.00977027
p_int: 0.984863949
p_ni: 0.015134877
p_wrong: 0.000001174
Score: 0.189
Data Source: BioPlex,STRINGDB
NAAA
Tchem
Family: Enzyme
Novelty: 0.00368876
p_int: 0.970053359
p_ni: 0.01095356
p_wrong: 0.018993081
Score: 0.213
Data Source: BioPlex,STRINGDB
ADAM18
Tdark
Family: Enzyme
Novelty: 0.22622379
p_int: 0.96979943
p_ni: 0.027827186
p_wrong: 0.002373384
Data Source: BioPlex
Publication Statistics
PubMed Score  22.53

PubMed score by year
PubTator Score  11.32

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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