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Tdark
KRI1
Protein KRI1 homolog

Protein Summary
Description
This gene overlaps with the gene for cysteine endopeptidase AUT-like 4 in a head-to-tail orientation. [provided by RefSeq, Jul 2008]
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
hub protein
0.9
drug perturbation
0.87
kinase perturbation
0.76
transcription factor perturbation
0.74
tissue sample
0.67


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.33   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.33   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
1
2
48
low density lipoprotein cholesterol measurement
1
1
2
43.2
neutrophil count
1
1
1
40
basophil count
2
1
2
25.1
neutrophil percentage of leukocytes
1
1
1
24.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
2
48
low density lipoprotein cholesterol measurement
2
43.2
neutrophil count
1
40
basophil count
2
25.1
neutrophil percentage of leukocytes
1
24.1
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (248)
1 – 10 of 248
RPS13
Tbio
Novelty: 0.0019983
p_int: 0.976878556
p_ni: 0.023121444
Data Source: BioPlex
RPS14
Tbio
Novelty: 0.00576737
p_int: 0.962957967
p_ni: 0.037042033
Score: 0.241
Data Source: BioPlex,STRINGDB
HIST1H1T
Tdark
Novelty: 0.01039464
p_int: 0.869551966
p_ni: 0.130448034
Score: 0.517
Data Source: BioPlex,STRINGDB
HIST1H1E
Tbio
Novelty: 0.01125284
p_int: 0.837126903
p_ni: 0.162873097
Score: 0.519
Data Source: BioPlex,STRINGDB
DAXX
Tbio
Novelty: 0.00348585
p_int: 0.81653103
p_ni: 0.18346897
Data Source: BioPlex
RNF151
Tdark
Novelty: 2.0077961
p_int: 0.805693385
p_ni: 0.194306615
Data Source: BioPlex
PDGFB
Tchem
Novelty: 0.00080876
p_int: 0.770038509
p_ni: 0.229961491
Data Source: BioPlex
ZCRB1
Tdark
Novelty: 0.37592387
p_int: 0.75541264
p_ni: 0.24458736
Score: 0.706
Data Source: BioPlex,STRINGDB
KRR1
Tbio
Novelty: 0.07965454
Score: 0.993
Data Source: STRINGDB
MPHOSPH10
Tbio
Novelty: 0.04846226
Score: 0.99
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.33

PubMed score by year
PubTator Score  5.13

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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