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Tdark
HARBI1
Putative nuclease HARBI1

Protein Summary
Description
Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326737
  • ENSP00000317743
  • ENSG00000180423

Symbol
  • C11orf77
  • C11orf77
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.88
cell type or tissue
0.87
transcription factor binding site profile
0.85
virus perturbation
0.72
cellular component
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.48   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 92   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.48   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 92   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking behaviour measurement
1
1
1
81.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking behaviour measurement
1
81.2
Gene Ontology Terms (6)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (20)
1 – 10 of 20
NAIF1
Tbio
Novelty: 0.1179429
p_int: 0.999750142
p_wrong: 0.000249858
Score: 0.964
Data Source: BioPlex,STRINGDB
QRICH1
Tdark
Novelty: 0.27714699
Score: 0.819
Data Source: STRINGDB
PGBD5
Tdark
Novelty: 0.15960609
Score: 0.795
Data Source: STRINGDB
THAP9
Tbio
Family: TF
Novelty: 0.25915023
Score: 0.767
Data Source: STRINGDB
ZMYM2
Tbio
Novelty: 0.0258698
Score: 0.729
Data Source: STRINGDB
GIN1
Tbio
Family: Enzyme
Novelty: 0.0247804
Score: 0.716
Data Source: STRINGDB
ZMYM3
Tbio
Novelty: 0.06911008
Score: 0.675
Data Source: STRINGDB
PTGR2
Tbio
Family: Enzyme
Novelty: 0.08766092
Score: 0.576
Data Source: STRINGDB
SFT2D2
Tdark
Novelty: 1.03145192
Score: 0.573
Data Source: STRINGDB
ZBED8
Tdark
Novelty: 2.26997341
Score: 0.558
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.48

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer