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Tdark
KIAA1551
Uncharacterized protein KIAA1551

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312561
  • ENSP00000310338
  • ENSG00000174718

Symbol
  • C12orf35
  • GET
  • UTA2-1
  • C12orf35
  • KIAA1551
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.86
kinase perturbation
0.84
transcription factor perturbation
0.84
cellular component
0.81
tissue
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.52   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.52   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
2
2
80.7
low density lipoprotein cholesterol measurement
1
1
1
58.5
1
1
0
1.2
55.6
red blood cell distribution width
1
1
1
54.8
eosinophil percentage of leukocytes
1
1
1
37
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
eosinophil count
2
80.7
low density lipoprotein cholesterol measurement
1
58.5
0
1.2
55.6
red blood cell distribution width
1
54.8
eosinophil percentage of leukocytes
1
37
Protein-Protein Interactions (18)
1 – 10 of 18
CALML3
Tbio
Novelty: 0.0336689
p_int: 0.999997829
p_ni: 0.000002171
Data Source: BioPlex
OR51B6
Tdark
Family: oGPCR
Novelty: 0.7834185
Score: 0.526
Data Source: STRINGDB
HMHB1
Tbio
Novelty: 0.47629958
Score: 0.511
Data Source: STRINGDB
NDC1
Tbio
Novelty: 0.15840853
Score: 0.479
Data Source: STRINGDB
BANF2
Tdark
Novelty: 0.13092902
Score: 0.475
Data Source: STRINGDB
ILKAP
Tbio
Family: Enzyme
Novelty: 0.13622259
Score: 0.475
Data Source: STRINGDB
STK31
Tchem
Family: Kinase
Novelty: 0.12405945
Score: 0.473
Data Source: STRINGDB
ZDHHC12
Tdark
Family: Enzyme
Novelty: 0.34034594
Score: 0.471
Data Source: STRINGDB
MTREX
Tbio
Novelty: 0.01358024
Score: 0.459
Data Source: STRINGDB
NUP58
Tbio
Novelty: 0.08797454
Score: 0.454
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.52

PubMed score by year
PubTator Score  1.92

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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