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Tbio
SLC5A6
Sodium-dependent multivitamin transporter

Protein Summary
Description
Transports pantothenate, biotin and lipoate in the presence of sodium.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000310574
  • ENSP00000310208
  • ENSG00000138074
  • ENST00000408041
  • ENSP00000384853

Symbol
  • SMVT
  • SMVT
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.9
pathway
0.85
disease perturbation
0.83
histone modification site profile
0.83
transcription factor binding site profile
0.78


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 81.69   (req: < 5)
Gene RIFs: 22   (req: <= 3)
Antibodies: 176   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 81.69   (req: >= 5)
Gene RIFs: 22   (req: > 3)
Antibodies: 176   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (37)
Biotin transport and metabolism (R-HSA-196780)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Biotin transport and metabolism
Reactome
Metabolism
Reactome
Metabolism of vitamins and cofactors
Reactome
Metabolism of water-soluble vitamins and cofactors
Reactome
SLC-mediated transmembrane transport
Name
Explore in Pharos
Explore in Source
Biotin transport and metabolism
Metabolism
Metabolism of vitamins and cofactors
Metabolism of water-soluble vitamins and cofactors
SLC-mediated transmembrane transport
Protein-Protein Interactions (40)
1 – 10 of 40
PDZK1P1
Tdark
p_int: 0.996398268
p_ni: 0.003601732
Data Source: BioPlex
PDZD11
Tbio
Novelty: 0.00896918
Score: 0.928
Data Source: Reactome,STRINGDB
HLCS
Tchem
Family: Enzyme
Novelty: 0.00489358
Score: 0.686
Data Source: STRINGDB
SLC16A5
Tdark
Family: Transporter
Novelty: 0.1216913
Score: 0.652
Data Source: STRINGDB
SLC17A1
Tbio
Family: Transporter
Novelty: 0.01817799
Score: 0.627
Data Source: STRINGDB
BTD
Tbio
Family: Enzyme
Novelty: 0.02283054
Score: 0.616
Data Source: STRINGDB
TBXT
Tbio
Family: TF
Novelty: 0.00479096
Score: 0.587
Data Source: STRINGDB
SLC37A1
Tbio
Family: Transporter
Novelty: 0.20022247
Score: 0.574
Data Source: STRINGDB
SLC16A9
Tbio
Family: Transporter
Novelty: 0.1256698
Score: 0.558
Data Source: STRINGDB
SLC22A12
Tclin
Family: Transporter
Novelty: 0.00100934
Score: 0.55
Data Source: STRINGDB
Publication Statistics
PubMed Score  81.69

PubMed score by year
PubTator Score  51.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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