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Tbio
LGI3
Leucine-rich repeat LGI family member 3

Protein Summary
Description
May participate in the regulation of neuronal exocytosis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306317
  • ENSP00000302297
  • ENSG00000168481
  • ENST00000424267
  • ENSP00000399121

Symbol
  • LGIL4
  • LGIL4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.69
tissue
0.6
gene perturbation
0.56
cellular component
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.74   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.74   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (2)
Developmental Biology (R-HSA-1266738)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 2 of 2
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Developmental Biology
Reactome
LGI-ADAM interactions
Name
Explore in Pharos
Explore in Source
Developmental Biology
LGI-ADAM interactions
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (60)
1 – 10 of 60
ADAM23
Tbio
Family: Enzyme
Novelty: 0.02974247
Score: 0.969
Data Source: Reactome,STRINGDB
ADAM22
Tbio
Family: Enzyme
Novelty: 0.01981755
Score: 0.966
Data Source: Reactome,STRINGDB
STX1B
Tbio
Novelty: 0.01171833
Score: 0.918
Data Source: Reactome,STRINGDB
STX1A
Tbio
Novelty: 0.00087207
Score: 0.915
Data Source: Reactome,STRINGDB
ADAM11
Tbio
Family: Enzyme
Novelty: 0.122537
Score: 0.676
Data Source: STRINGDB
MTUS1
Tbio
Novelty: 0.01066081
Score: 0.624
Data Source: STRINGDB
ADAM28
Tbio
Family: Enzyme
Novelty: 0.01239522
Score: 0.604
Data Source: STRINGDB
GABRD
Tclin
Family: IC
Novelty: 0.0204242
Score: 0.582
Data Source: STRINGDB
SYT4
Tbio
Novelty: 0.01527865
Score: 0.579
Data Source: STRINGDB
PHYHIP
Tdark
Family: Enzyme
Novelty: 0.25773185
Score: 0.577
Data Source: STRINGDB
Publication Statistics
PubMed Score  18.74

PubMed score by year
PubTator Score  8.61

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer