You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SNRK
SNF-related serine/threonine-protein kinase

Protein Summary
Description
May play a role in hematopoietic cell proliferation or differentiation. Potential mediator of neuronal apoptosis. SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296088
  • ENSP00000296088
  • ENSG00000163788
  • ENST00000429705
  • ENSP00000411375
  • ENST00000454177
  • ENSP00000401246

Symbol
  • KIAA0096
  • SNFRK
  • HSNFRK
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
disease perturbation
0.96
molecular function
0.94
protein domain
0.85
virus perturbation
0.85


Related Tools
ProKinO
The ProKinO is a protein kinase-specific ontology, which provides a controlled vocabulary of terms, their hierarchy, and relationships unifying sequence, structure, function, mutation and pathway information on kinases.
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.56   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 142   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 137.56   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1
16.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1
16.2
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
SNF related kinase
VGNC:2567
460301
Macaque
SNF related kinase
715803
Mouse
MGI:108104
20623
Rat
RGD:69653
170837
Dog
SNF related kinase
477011
Species
Name
OMA
EggNOG
Inparanoid
Chimp
SNF related kinase
Macaque
SNF related kinase
Mouse
Rat
Dog
SNF related kinase
Protein Structure (1 Structure, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q9NRH2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Protein-Protein Interactions (26)
1 – 10 of 26
ADAMTS12
Tbio
Family: Enzyme
Novelty: 0.03184816
p_int: 0.999999983
p_ni: 1.5e-8
p_wrong: 2e-9
Score: 0.651
Data Source: BioPlex,STRINGDB
GDF5
Tbio
Novelty: 0.00218118
p_int: 0.999999949
p_ni: 1.1e-8
p_wrong: 3.9e-8
Score: 0.189
Data Source: BioPlex,STRINGDB
ABHD5
Tbio
Family: Enzyme
Novelty: 0.00806614
p_int: 0.989606359
p_ni: 0.005973322
p_wrong: 0.004420319
Score: 0.325
Data Source: BioPlex,STRINGDB
DUSP5
Tbio
Family: Enzyme
Novelty: 0.00197547
Score: 0.763
Data Source: STRINGDB
CAB39
Tbio
Novelty: 0.01592402
Score: 0.744
Data Source: STRINGDB
DUSP2
Tbio
Family: Enzyme
Novelty: 0.03459749
Score: 0.712
Data Source: STRINGDB
SFRP4
Tbio
Novelty: 0.00174428
Score: 0.669
Data Source: STRINGDB
PDP1
Tbio
Family: Enzyme
Novelty: 0.00442352
Score: 0.668
Data Source: STRINGDB
HEY2
Tbio
Family: TF
Novelty: 0.00569776
Score: 0.641
Data Source: STRINGDB
DUSP1
Tchem
Family: Enzyme
Novelty: 0.00097955
Score: 0.577
Data Source: STRINGDB
Publication Statistics
PubMed Score  137.56

PubMed score by year
PubTator Score  10.82

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: