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Tdark
FAM71A
Protein FAM71A

Protein Summary
Description
This gene encodes a protein that interacts with the Rab2B small GTPase and may be important for integrity of the Golgi body. A knockdown of this gene induces fragmentation of the Golgi, similar to the effect seen with a knockdown of the Rab2B small GTPase. The encoded protein has an N-terminal Rab-binding domain specific for Rab2B. [provided by RefSeq, Feb 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294829
  • ENSP00000294829
  • ENSG00000162771

Symbol
  • GARI-L4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.76
cell line
0.7
cell type or tissue
0.36
cellular component
0.32
virus perturbation
0.32


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.46   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 71 member A
VGNC:6812
746300
Mouse
MGI:3588202
619288
Rat
RGD:1561646
498311
Dog
family with sequence similarity 71 member A
VGNC:53348
111089968
Cow
family with sequence similarity 71 member A
616153
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 71 member A
Mouse
Rat
Dog
family with sequence similarity 71 member A
Cow
family with sequence similarity 71 member A
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IYT1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (16)
1 – 10 of 16
NPIPA5
Tdark
Novelty: 2.65384615
Score: 0.669
Data Source: STRINGDB
PEBP4
Tbio
Novelty: 0.03634897
Score: 0.652
Data Source: STRINGDB
RAB2B
Tdark
Family: Enzyme
Novelty: 0.18567584
Score: 0.639
Data Source: STRINGDB
MORN5
Tdark
Novelty: 1.51123721
Score: 0.635
Data Source: STRINGDB
EFR3A
Tbio
Novelty: 0.17687362
Score: 0.615
Data Source: STRINGDB
CCNYL1
Tdark
Novelty: 0.45350824
Score: 0.546
Data Source: STRINGDB
C2orf73
Tdark
Novelty: 0.8689571
Score: 0.514
Data Source: STRINGDB
KBTBD7
Tdark
Novelty: 0.4947466
Score: 0.479
Data Source: STRINGDB
INTS6L
Tdark
Novelty: 1.91229606
Score: 0.473
Data Source: STRINGDB
SPEF2
Tdark
Novelty: 0.03559091
Score: 0.466
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.46

PubMed score by year
PubTator Score  0.67

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer