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Tbio
FLAD1
FAD synthase

Protein Summary
Description
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000292180
  • ENSP00000292180
  • ENSG00000160688
  • ENST00000315144
  • ENSP00000317296
  • ENST00000368431
  • ENSP00000357416
  • ENST00000368432
  • ENSP00000357417

Symbol
  • FAD1
  • FADS
  • PP591
  • LSMFLAD
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
disease perturbation
0.79
transcription factor binding site profile
0.77
transcription factor
0.72
kinase perturbation
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.21   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 141   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 45.21   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 141   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (22)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Metabolism of vitamins and cofactors
Reactome
Metabolism of water-soluble vitamins and cofactors
Reactome
Vitamin B2 (riboflavin) metabolism
Name
Explore in Pharos
Explore in Source
Metabolism
Metabolism of vitamins and cofactors
Metabolism of water-soluble vitamins and cofactors
Vitamin B2 (riboflavin) metabolism
Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (70)
1 – 10 of 70
FAM19A3
Tdark
Novelty: 0.37183557
p_int: 0.999997957
p_ni: 0.000002043
Data Source: BioPlex
PLEKHO2
Tdark
Novelty: 0.48296621
p_int: 0.999854038
p_ni: 0.000145962
Score: 0.243
Data Source: BioPlex,STRINGDB
ANKRD39
Tdark
Novelty: 8.68843298
p_int: 0.998289404
p_ni: 0.001710592
p_wrong: 4e-9
Data Source: BioPlex
FSCN3
Tdark
Novelty: 0.28942634
p_int: 0.9979932
p_ni: 0.0020068
p_wrong: 1e-9
Score: 0.379
Data Source: BioPlex,STRINGDB
KLHL14
Tbio
Novelty: 0.1214402
p_int: 0.996020846
p_ni: 0.003979154
Score: 0.346
Data Source: BioPlex,STRINGDB
BICD2
Tbio
Novelty: 0.01725046
p_int: 0.990779857
p_ni: 0.009217289
p_wrong: 0.000002855
Data Source: BioPlex
SPANXN4
Tdark
Novelty: 1.91062423
p_int: 0.987353517
p_ni: 0.012645658
p_wrong: 8.25e-7
Data Source: BioPlex
C6orf222
Tdark
Novelty: 37
p_int: 0.976407908
p_ni: 0.005062904
p_wrong: 0.018529188
Data Source: BioPlex
GREM2
Tbio
Novelty: 0.01839564
p_int: 0.966243025
p_ni: 0.033748451
p_wrong: 0.000008524
Data Source: BioPlex
CARTPT
Tbio
Novelty: 0.00224864
p_int: 0.966243025
p_ni: 0.033748451
p_wrong: 0.000008524
Data Source: BioPlex
Publication Statistics
PubMed Score  45.21

PubMed score by year
PubTator Score  49.05

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer