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Tdark
C4orf19
Uncharacterized protein C4orf19

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000284437
  • ENSP00000284437
  • ENSG00000154274
  • ENST00000381980
  • ENSP00000371408
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.31   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
STK24
Tchem
Family:  Kinase
Novelty:  0.00457236
p_int:  0.999999214
p_ni:  7.86e-7
Score:  0.864
Data Source:  BioPlex,STRINGDB
PDCD10
Tbio
Novelty:  0.00683934
p_int:  0.999997599
p_ni:  0.000002401
Score:  0.86
Data Source:  BioPlex,STRINGDB
STK25
Tchem
Family:  Kinase
Novelty:  0.03229688
p_int:  0.999931632
p_ni:  0.000068368
Score:  0.826
Data Source:  BioPlex,STRINGDB
STK26
Tchem
Family:  Kinase
Novelty:  0.03633178
p_int:  0.999864854
p_ni:  0.000135146
Score:  0.836
Data Source:  BioPlex,STRINGDB
EEF1A2
Tchem
Novelty:  0.001472
p_int:  0.864466628
p_ni:  0.135533371
Data Source:  BioPlex
CORO1C
Tbio
Novelty:  0.02068813
Score:  0.682
Data Source:  STRINGDB
ISM1
Tbio
Novelty:  0.03082946
Score:  0.677
Data Source:  STRINGDB
FAM219B
Tdark
Novelty:  5.26378794
Score:  0.59
Data Source:  STRINGDB
FAM221A
Tdark
Novelty:  1.40181414
Score:  0.588
Data Source:  STRINGDB
TTMP
Tdark
Novelty:  0.22491726
Score:  0.581
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
1
1
1
67.1
1
1
0
1.4
38.2
1
1
0
1.4
38.2
serum gamma-glutamyl transferase measurement
1
1
1
35
sex hormone-binding globulin measurement
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
1
67.1
0
1.4
38.2
0
1.4
38.2
serum gamma-glutamyl transferase measurement
1
35
sex hormone-binding globulin measurement
1
31.4
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 4 C4orf19 homolog
VGNC:10826
736131
Macaque
chromosome 5 open reading frame, human C4orf19
697118
Mouse
MGI:1923511
76261
Rat
RGD:1561612
498368
Dog
chromosome 3 C4orf19 homolog
VGNC:53156
102152184
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 4 C4orf19 homolog
Macaque
chromosome 5 open reading frame, human C4orf19
Mouse
Rat
Dog
chromosome 3 C4orf19 homolog
Publication Statistics
PubMed Score 0.31
PubMed score by year
PubTator Score 0.25
PubTator score by year
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Related Publications
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PMID
Year
Title