You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TMEM18
Transmembrane protein 18

Protein Summary
Description
Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000281017
  • ENSP00000281017
  • ENSG00000151353
  • ENST00000355654
  • ENSP00000347874

Symbol
  • lncND
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.83
transcription factor binding site profile
0.8
cell type or tissue
0.79
histone modification site profile
0.78
transcription factor
0.69


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 43.17   (req: < 5)
Gene RIFs: 27   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 43.17   (req: >= 5)
Gene RIFs: 27   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 18
VGNC:398
749386
Mouse
MGI:2387176
211986
Rat
RGD:1359389
362722
Horse
transmembrane protein 18
VGNC:51417
100073041
Cow
transmembrane protein 18
VGNC:36006
616554
Species
Name
OMA
EggNOG
Inparanoid
Chimp
transmembrane protein 18
Mouse
Rat
Horse
transmembrane protein 18
Cow
transmembrane protein 18
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q96B42-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (58)
1 – 10 of 58
GNPDA2
Tbio
Family: Enzyme
Novelty: 0.02712908
Score: 0.891
Data Source: STRINGDB
KCTD15
Tbio
Novelty: 0.05277304
Score: 0.87
Data Source: STRINGDB
FTO
Tbio
Family: Enzyme
Novelty: 0.00053473
Score: 0.861
Data Source: STRINGDB
NEGR1
Tbio
Novelty: 0.0088917
Score: 0.86
Data Source: STRINGDB
SEC16B
Tbio
Novelty: 0.04073621
Score: 0.841
Data Source: STRINGDB
SH2B1
Tbio
Novelty: 0.01659457
Score: 0.838
Data Source: STRINGDB
MTCH2
Tbio
Novelty: 0.01794294
Score: 0.837
Data Source: STRINGDB
MC4R
Tclin
Family: GPCR
Novelty: 0.00091593
Score: 0.831
Data Source: STRINGDB
FAIM2
Tbio
Novelty: 0.02444421
Score: 0.732
Data Source: STRINGDB
ETV5
Tbio
Family: TF
Novelty: 0.00052506
Score: 0.676
Data Source: STRINGDB
Publication Statistics
PubMed Score  43.17

PubMed score by year
PubTator Score  29.01

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: