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Tbio
FSIP1
Fibrous sheath-interacting protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000350221
  • ENSP00000280236
  • ENSG00000150667

Symbol
  • HSD10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.66
disease perturbation
0.62
trait
0.61
transcription factor binding site profile
0.55
cell line
0.5


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.97   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 51.97   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
1
1
0
8.5
70.1
urate measurement
1
1
2
64.7
serum gamma-glutamyl transferase measurement
1
1
1
6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
0
8.5
70.1
urate measurement
2
64.7
serum gamma-glutamyl transferase measurement
1
6
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
fibrous sheath interacting protein 1
VGNC:3552
737356
Macaque
fibrous sheath interacting protein 1
701001
Mouse
MGI:1918563
71313
Rat
RGD:1306874
296074
Dog
fibrous sheath interacting protein 1
VGNC:40998
478256
Species
Name
OMA
EggNOG
Inparanoid
Chimp
fibrous sheath interacting protein 1
Macaque
fibrous sheath interacting protein 1
Mouse
Rat
Dog
fibrous sheath interacting protein 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NA03-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (61)
1 – 10 of 61
HSD17B10
Tchem
Family: Enzyme
Novelty: 0.00486582
Score: 0.834
Data Source: STRINGDB
AKAP4
Tbio
Family: Enzyme
Novelty: 0.00760557
Score: 0.818
Data Source: STRINGDB
FSIP2
Tdark
Novelty: 0.16245939
Score: 0.81
Data Source: STRINGDB
DHRS11
Tbio
Family: Enzyme
Novelty: 0.00352776
Score: 0.757
Data Source: STRINGDB
TRMT10C
Tbio
Family: Enzyme
Novelty: 0.07045719
Score: 0.71
Data Source: STRINGDB
KIAA0391
Tbio
Family: Enzyme
Novelty: 0.02276396
Score: 0.669
Data Source: STRINGDB
AKAP3
Tbio
Family: Enzyme
Novelty: 0.030936
Score: 0.66
Data Source: STRINGDB
RIBC1
Tdark
Novelty: 0.40435429
Score: 0.655
Data Source: STRINGDB
HADH
Tbio
Family: Enzyme
Novelty: 0.00368073
Score: 0.63
Data Source: STRINGDB
ROPN1
Tbio
Novelty: 0.05375245
Score: 0.607
Data Source: STRINGDB
Publication Statistics
PubMed Score  51.97

PubMed score by year
PubTator Score  22.9

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer