Protein Summary
Possible role in granule neuron development.
- ENST00000273596
- ENSP00000273596
- ENSG00000248487
- DORZ1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 0.95 | ||
histone modification site profile | 0.79 | ||
transcription factor perturbation | 0.68 | ||
gene perturbation | 0.65 | ||
tissue | 0.61 | ||
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.57 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 120 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 0.57 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 120 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 1
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Gene Ontology Terms (3)
Functions (1)
Components (2)
Items per page:
10
1 – 1 of 1
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Protein-Protein Interactions (55)
1 – 10 of 55
SLC39A12
Family: Transporter
Novelty: 0.11255353
p_int: 0.984870979
p_ni: 0.015125871
p_wrong: 0.00000315
Data Source: BioPlex
IL13RA2
Novelty: 0.04900852
p_int: 0.969797827
p_ni: 0.03020216
p_wrong: 1.3e-8
Data Source: BioPlex
CEACAM21
Novelty: 0.98765432
p_int: 0.961374736
p_ni: 0.038625217
p_wrong: 4.7e-8
Data Source: BioPlex
SCARA3
Novelty: 0.00826861
p_int: 0.949631709
p_ni: 0.050368291
Data Source: BioPlex
CD1E
Novelty: 0.00231902
p_int: 0.927536271
p_ni: 0.072463729
Data Source: BioPlex
SLC39A5
Family: Transporter
Novelty: 0.06778122
p_int: 0.926359192
p_ni: 0.073640808
Data Source: BioPlex
A4GALT
Family: Enzyme
Novelty: 0.00253249
p_int: 0.894867248
p_ni: 0.105122593
p_wrong: 0.000010159
Score: 0.252
Data Source: BioPlex,STRINGDB
GGT7
Family: Enzyme
Novelty: 0.0180475
p_int: 0.880854649
p_ni: 0.119111568
p_wrong: 0.000033783
Score: 0.153
Data Source: BioPlex,STRINGDB
TCTN2
Novelty: 0.19568118
p_int: 0.87320657
p_ni: 0.126793412
p_wrong: 1.8e-8
Data Source: BioPlex
CHRNB4
Family: IC
Novelty: 0.02388015
p_int: 0.872444896
p_ni: 0.098491678
p_wrong: 0.029063426
Data Source: BioPlex
Publication Statistics
PubMed Score 0.57
PubMed score by year
PubTator Score 0.09
PubTator score by year
Amino Acid Sequence
Residue Counts
Sequence
MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTV
1-70
LAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPS
70-140
KEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAV
140-210
KTPTLILYGELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP
210-271
MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP
Find similar targets by: