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Tbio
CBLN2
Cerebellin-2

Protein Summary
Description
May play role in synaptogenesis induction.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000269503
  • ENSP00000269503
  • ENSG00000141668
  • ENST00000585159
  • ENSP00000463771
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.78
PubMedID
0.62
transcription factor perturbation
0.54
cell line
0.5
cell type or tissue
0.48


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.41   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 157   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.41   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 157   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolic syndrome
1
1
1
33.6
bilirubin measurement
1
1
1
33.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
metabolic syndrome
1
33.6
bilirubin measurement
1
33.6
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cerebellin 2 precursor
VGNC:7312
468579
Macaque
cerebellin 2 precursor
694193
Mouse
MGI:88282
12405
Rat
RGD:1309715
291388
Dog
cerebellin 2 precursor
VGNC:38762
483936
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cerebellin 2 precursor
Macaque
cerebellin 2 precursor
Mouse
Rat
Dog
cerebellin 2 precursor
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8IUK8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (51)
1 – 10 of 51
LHX9
Tbio
Family: TF
Novelty: 0.02952374
Score: 0.694
Data Source: STRINGDB
EMX2
Tbio
Family: TF
Novelty: 0.0064759
Score: 0.689
Data Source: STRINGDB
NPY
Tbio
Novelty: 0.00012637
Score: 0.682
Data Source: STRINGDB
ABCA8
Tbio
Family: Transporter
Novelty: 0.0698037
Score: 0.668
Data Source: STRINGDB
CRYM
Tbio
Family: Enzyme
Novelty: 0.02044871
Score: 0.661
Data Source: STRINGDB
NR4A2
Tchem
Family: NR
Novelty: 0.00204712
Score: 0.655
Data Source: STRINGDB
BAIAP2
Tbio
Novelty: 0.00949996
Score: 0.648
Data Source: STRINGDB
KIF18A
Tbio
Novelty: 0.02071108
Score: 0.626
Data Source: STRINGDB
PDGFD
Tbio
Novelty: 0.00799996
Score: 0.621
Data Source: STRINGDB
NRXN2
Tbio
Novelty: 0.01252742
Score: 0.602
Data Source: STRINGDB
Publication Statistics
PubMed Score  11.41

PubMed score by year
PubTator Score  4.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer