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Tdark
ZCCHC2
Zinc finger CCHC domain-containing protein 2

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.02   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 20   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.02   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 20   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
2
1
1
1
81.6
C-reactive protein measurement
1
1
1
70.9
self reported educational attainment
1
1
1
52
stressful life event measurement
2
1
2
37
depressive symptom measurement
2
1
2
37
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
1
81.6
C-reactive protein measurement
1
70.9
self reported educational attainment
1
52
stressful life event measurement
2
37
depressive symptom measurement
2
37
Gene Ontology Terms (4)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (44)
1 – 10 of 44
CMTR1
Tbio
Family: Enzyme
Novelty: 0.09259694
Score: 0.682
Data Source: STRINGDB
DDX6
Tbio
Family: Enzyme
Novelty: 0.01032357
Score: 0.592
Data Source: STRINGDB
UTP15
Tbio
Novelty: 0.08174586
Score: 0.582
Data Source: STRINGDB
LYSMD2
Tdark
Novelty: 3.17245408
Score: 0.582
Data Source: STRINGDB
RELCH
Tdark
Novelty: 0.33696386
Score: 0.57
Data Source: STRINGDB
FBXO16
Tdark
Novelty: 0.60353147
Score: 0.556
Data Source: STRINGDB
USP38
Tbio
Family: Enzyme
Novelty: 0.10350208
Score: 0.555
Data Source: STRINGDB
GTPBP4
Tbio
Novelty: 0.00062563
Score: 0.552
Data Source: STRINGDB
PHACTR2
Tbio
Family: Enzyme
Novelty: 0.25056698
Score: 0.549
Data Source: STRINGDB
NKAPD1
Tdark
Novelty: 1.56979675
Score: 0.546
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.02

PubMed score by year
PubTator Score  0.28

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer