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Tdark
ANP32D
Acidic leucine-rich nuclear phosphoprotein 32 family member D

Protein Summary
Description
Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000266594
  • ENSP00000266594
  • ENSG00000139223

Symbol
  • PP32R2
  • PP32R2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.73
protein complex
0.43
cell line
0.4
tissue
0.37
interacting protein
0.31


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.94   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 51   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.94   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 51   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-O95626-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (14)
1 – 10 of 14
SENP1
Tchem
Family: Enzyme
Novelty: 0.00831213
Score: 0.642
Data Source: STRINGDB
OR12D3
Tdark
Family: oGPCR
Novelty: 2.8827767
Score: 0.559
Data Source: STRINGDB
RBM17
Tbio
Novelty: 0.04840999
Score: 0.51
Data Source: STRINGDB
H2AFZ
Tbio
Novelty: 0.00222512
Score: 0.484
Data Source: STRINGDB
H2AFV
Tbio
Novelty: 0.03561635
Score: 0.478
Data Source: STRINGDB
GTF3C6
Tdark
Novelty: 1.44154731
Score: 0.47
Data Source: STRINGDB
EPAS1
Tchem
Novelty: 0.00307448
Score: 0.446
Data Source: STRINGDB
EGLN1
Tclin
Novelty: 0.00236525
Score: 0.445
Data Source: STRINGDB
IARS
Tchem
Family: Enzyme
Novelty: 0.00539046
Score: 0.442
Data Source: STRINGDB
PAK1IP1
Tbio
Family: Enzyme
Novelty: 0.07757993
Score: 0.442
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.94

PubMed score by year
PubTator Score  3.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer