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Tbio
FAM13A
Protein FAM13A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000264344
  • ENSP00000264344
  • ENSG00000138640
  • ENST00000395002
  • ENSP00000378450
  • ENST00000503556
  • ENSP00000427189
  • ENST00000508369
  • ENSP00000421562
  • ENST00000513837
  • ENSP00000423252

Symbol
  • FAM13A1
  • KIAA0914
  • FAM13A1
  • ARHGAP48
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
phenotype
0.85
transcription factor
0.74
kinase perturbation
0.66
microRNA
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.03   (req: < 5)
Gene RIFs: 21   (req: <= 3)
Antibodies: 35   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 42.03   (req: >= 5)
Gene RIFs: 21   (req: > 3)
Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (23)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
9
3
13
99.3
9
8
0
1.3
97.8
waist-hip ratio
2
2
2
97.6
high density lipoprotein cholesterol measurement
5
4
8
94
sex hormone-binding globulin measurement
3
1
3
90.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
13
99.3
0
1.3
97.8
waist-hip ratio
2
97.6
high density lipoprotein cholesterol measurement
8
94
sex hormone-binding globulin measurement
3
90.8
Pathways (16)
Rho GTPase cycle (R-HSA-194840)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Rho GTPase cycle
Reactome
Signal Transduction
Reactome
Signaling by Rho GTPases
Name
Explore in Pharos
Explore in Source
Rho GTPase cycle
Signal Transduction
Signaling by Rho GTPases
Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (84)
1 – 10 of 84
UNC119
Tchem
Novelty: 0.00396292
p_int: 0.999999992
p_ni: 8e-9
Score: 0.232
Data Source: BioPlex,STRINGDB
AHCYL1
Tchem
Family: Enzyme
Novelty: 0.02176432
p_int: 0.999990145
p_ni: 0.000006754
p_wrong: 0.000003101
Data Source: BioPlex
TBCCD1
Tbio
Novelty: 0.21991508
p_int: 0.999893475
p_ni: 0.0000158
p_wrong: 0.000090725
Score: 0.297
Data Source: BioPlex,STRINGDB
RHOA
Tbio
Family: Enzyme
Novelty: 0.00022204
Score: 0.925
Data Source: STRINGDB
RAC2
Tbio
Family: Enzyme
Novelty: 0.00116234
Score: 0.916
Data Source: STRINGDB
RHOJ
Tbio
Family: Enzyme
Novelty: 0.01217051
Score: 0.915
Data Source: STRINGDB
RHOU
Tbio
Family: Enzyme
Novelty: 0.01456329
Score: 0.915
Data Source: STRINGDB
RHOBTB1
Tbio
Novelty: 0.02152609
Score: 0.915
Data Source: STRINGDB
RHOQ
Tbio
Family: Enzyme
Novelty: 0.00562425
Score: 0.914
Data Source: STRINGDB
RHOBTB2
Tbio
Novelty: 0.00734789
Score: 0.914
Data Source: STRINGDB
Publication Statistics
PubMed Score  42.03

PubMed score by year
PubTator Score  24.14

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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