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Tbio
MYBPH
Myosin-binding protein H

Protein Summary
Description
Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000255416
  • ENSP00000255416
  • ENSG00000133055
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
gene perturbation
0.76
PubMedID
0.52
transcription factor
0.52
cell line
0.44


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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 387.05   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 189   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 387.05   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 189   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
myosin binding protein H
VGNC:11550
457639
Macaque
myosin binding protein H
703516
Mouse
MGI:1858196
53311
Rat
RGD:620287
83708
Dog
myosin binding protein H
VGNC:43525
490223
Species
Name
OMA
EggNOG
Inparanoid
Chimp
myosin binding protein H
Macaque
myosin binding protein H
Mouse
Rat
Dog
myosin binding protein H
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q13203-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Protein-Protein Interactions (92)
1 – 10 of 92
GCSH
Tbio
Novelty: 0.02101972
Score: 0.902
Data Source: STRINGDB
AMT
Tbio
Family: Enzyme
Novelty: 0.00796968
Score: 0.883
Data Source: STRINGDB
MYL1
Tbio
Novelty: 0.00360262
Score: 0.875
Data Source: STRINGDB
CD46
Tbio
Novelty: 0.00098341
Score: 0.841
Data Source: STRINGDB
MYLPF
Tbio
Novelty: 0.00960325
Score: 0.808
Data Source: STRINGDB
GLDC
Tbio
Family: Enzyme
Novelty: 0.00900467
Score: 0.8
Data Source: STRINGDB
TNNC2
Tbio
Novelty: 0.07759506
Score: 0.778
Data Source: STRINGDB
MYH15
Tbio
Novelty: 0.01139168
Score: 0.767
Data Source: STRINGDB
MYH14
Tbio
Novelty: 0.00874871
Score: 0.75
Data Source: STRINGDB
MYH4
Tbio
Novelty: 0.00556982
Score: 0.738
Data Source: STRINGDB
Publication Statistics
PubMed Score  387.05

PubMed score by year
PubTator Score  46.76

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer