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Tbio
ANGPTL6
Angiopoietin-related protein 6

Protein Classes
Protein Summary
Description
May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000253109
  • ENSP00000253109
  • ENSG00000130812
  • ENST00000592641
  • ENSP00000467930

Symbol
  • AGF
  • ARP5
  • AGF
  • ARP5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.63
protein domain
0.58
tissue sample
0.58
cell type or tissue
0.54
disease
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 185.44   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 172   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 185.44   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 172   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (17)
1 – 10 of 17
ANGPTL8
Tbio
Novelty: 0.00622889
Score: 0.707
Data Source: STRINGDB
RYDEN
Tdark
Novelty: 0.17308437
Score: 0.691
Data Source: STRINGDB
ITGA2B
Tclin
Novelty: 0.00023168
Score: 0.624
Data Source: STRINGDB
LPL
Tchem
Family: Enzyme
Novelty: 0.00057058
Score: 0.556
Data Source: STRINGDB
GMDS
Tbio
Family: Enzyme
Novelty: 0.00622275
Score: 0.551
Data Source: STRINGDB
TGM6
Tchem
Family: Enzyme
Novelty: 0.00766073
Score: 0.527
Data Source: STRINGDB
ART5
Tbio
Family: Enzyme
Novelty: 0.07566514
Score: 0.469
Data Source: STRINGDB
GPR45
Tbio
Family: GPCR
Novelty: 0.08366919
Score: 0.461
Data Source: STRINGDB
FGF21
Tbio
Novelty: 0.00111728
Score: 0.434
Data Source: STRINGDB
LINGO2
Tbio
Novelty: 0.06112205
Score: 0.43
Data Source: STRINGDB
Publication Statistics
PubMed Score  185.44

PubMed score by year
PubTator Score  46.98

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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