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Tbio
AFTPH
Aftiphilin

Protein Summary
Description
May play a role in membrane trafficking.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000238855
  • ENSP00000238855
  • ENSG00000119844
  • ENST00000238856
  • ENSP00000238856
  • ENST00000409933
  • ENSP00000387071

Symbol
  • AFTH
  • Nbla10388
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.97
virus perturbation
0.92
transcription factor binding site profile
0.91
histone modification site profile
0.85
transcription factor perturbation
0.84


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.18   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Protein-Protein Interactions (88)
1 – 10 of 88
AP1S2
Tbio
Novelty: 0.01413503
p_int: 0.999999999
Score: 0.934
Data Source: BioPlex,STRINGDB
AP1S3
Tbio
Novelty: 0.14425094
p_int: 0.999999991
p_ni: 6e-9
p_wrong: 3e-9
Score: 0.552
Data Source: BioPlex,STRINGDB
VAPB
Tbio
Novelty: 0.00542377
p_int: 0.999997722
p_ni: 0.000002274
p_wrong: 5e-9
Score: 0.19
Data Source: BioPlex,STRINGDB
VAPA
Tbio
Novelty: 0.00169209
p_int: 0.999896248
p_ni: 0.000102818
p_wrong: 9.34e-7
Score: 0.252
Data Source: BioPlex,STRINGDB
AP1M2
Tbio
Novelty: 0.02984354
p_int: 0.97908955
p_ni: 0.00090943
p_wrong: 0.020001019
Score: 0.889
Data Source: BioPlex,STRINGDB
AP1G2
Tbio
Novelty: 0.17203425
Score: 0.955
Data Source: STRINGDB
AP4E1
Tdark
Novelty: 0.09773225
Score: 0.932
Data Source: STRINGDB
SCYL1
Tbio
Family: Kinase
Novelty: 0.03774351
Score: 0.925
Data Source: STRINGDB
AP2A1
Tbio
Novelty: 0.08554974
Score: 0.92
Data Source: STRINGDB
AP4M1
Tbio
Novelty: 0.00142961
Score: 0.912
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.18

PubMed score by year
PubTator Score  3.1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer