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Tbio
FGFR1OP2
FGFR1 oncogene partner 2

Protein Summary
Description
May be involved in wound healing pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000229395
  • ENSP00000229395
  • ENSG00000111790
  • ENST00000327214
  • ENSP00000323763
  • ENST00000546072
  • ENSP00000437556

Symbol
  • WIT3.0
  • HSPC123-like
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
cell type or tissue
0.86
histone modification site profile
0.86
virus perturbation
0.76
transcription factor binding site profile
0.63


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 198   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 198   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (6)
Disease (R-HSA-1643685)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Disease
Reactome
Diseases of signal transduction
Reactome
FGFR1 mutant receptor activation
Reactome
Signaling by FGFR in disease
Reactome
Signaling by FGFR1 in disease
Name
Explore in Pharos
Explore in Source
Disease
Diseases of signal transduction
FGFR1 mutant receptor activation
Signaling by FGFR in disease
Signaling by FGFR1 in disease
Protein-Protein Interactions (91)
1 – 10 of 91
TRAF3IP3
Tbio
Novelty: 0.22909091
p_int: 1
Score: 0.86
Data Source: BioPlex,STRINGDB
RGPD8
Tdark
Novelty: 0.25609756
p_int: 0.999999379
p_ni: 6.21e-7
Data Source: BioPlex
TNFRSF1A
Tchem
Novelty: 0.00048442
p_int: 0.999998959
p_ni: 0.000001041
Data Source: BioPlex
SLMAP
Tbio
Novelty: 0.04279507
p_int: 0.999991223
p_ni: 0.000008777
Score: 0.883
Data Source: BioPlex,STRINGDB
RGPD5
Tdark
Novelty: 0.26241703
p_int: 0.99998618
p_ni: 0.00001382
Data Source: BioPlex
CCHCR1
Tbio
Novelty: 0.01110278
p_int: 0.999982537
p_ni: 0.000017463
Data Source: BioPlex
PPP2CB
Tbio
Family: Enzyme
Novelty: 0.06629168
p_int: 0.999973816
p_ni: 0.000026155
p_wrong: 2.9e-8
Score: 0.454
Data Source: BioPlex,STRINGDB
PPP2R1A
Tbio
Family: Enzyme
Novelty: 0.01848436
p_int: 0.999944796
p_ni: 0.000055128
p_wrong: 7.6e-8
Score: 0.414
Data Source: BioPlex,STRINGDB
RABEP2
Tdark
Family: Enzyme
Novelty: 0.26638478
p_int: 0.999936729
p_ni: 0.000063271
Data Source: BioPlex
PLP1
Tbio
Novelty: 0.00162008
p_int: 0.999905309
p_ni: 0.000094666
p_wrong: 2.5e-8
Score: 0.196
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  8.53

PubMed score by year
PubTator Score  10.99

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer