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Tbio
CCDC80
Coiled-coil domain-containing protein 80

Protein Summary
Description
Promotes cell adhesion and matrix assembly.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000206423
  • ENSP00000206423
  • ENSG00000091986
  • ENST00000439685
  • ENSP00000411814

Symbol
  • DRO1
  • URB
  • CL2
  • URB
  • DRO1
  • SSG1
  • okuribin
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
small molecule perturbation
0.87
cell type or tissue
0.64
tissue sample
0.58
PubMedID
0.51


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.43   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.43   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
44
1
1
0
1.3
29.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
44
0
1.3
29.5
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 80
VGNC:11363
460586
Macaque
coiled-coil domain containing 80
708504
Mouse
MGI:1915146
67896
Rat
RGD:69421
64387
Dog
coiled-coil domain containing 80
VGNC:38858
478566
Species
Name
OMA
EggNOG
Inparanoid
Chimp
coiled-coil domain containing 80
Macaque
coiled-coil domain containing 80
Mouse
Rat
Dog
coiled-coil domain containing 80
Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (37)
1 – 10 of 37
BRS3
Tchem
Family: GPCR
Novelty: 0.00520417
Score: 0.909
Data Source: STRINGDB
FAAH
Tchem
Family: Enzyme
Novelty: 0.00162361
Score: 0.764
Data Source: STRINGDB
CNR1
Tclin
Family: GPCR
Novelty: 0.00060063
Score: 0.698
Data Source: STRINGDB
TEPP
Tdark
Novelty: 0.16848204
Score: 0.626
Data Source: STRINGDB
COL1A2
Tbio
Novelty: 0.00048334
Score: 0.61
Data Source: STRINGDB
MGLL
Tchem
Family: Enzyme
Novelty: 0.00196912
Score: 0.584
Data Source: STRINGDB
COL9A3
Tbio
Novelty: 0.02556037
Score: 0.57
Data Source: STRINGDB
URB2
Tbio
Novelty: 0.0837511
Score: 0.567
Data Source: STRINGDB
COL3A1
Tbio
Novelty: 0.00197327
Score: 0.566
Data Source: STRINGDB
COL5A1
Tbio
Novelty: 0.00506815
Score: 0.526
Data Source: STRINGDB
Publication Statistics
PubMed Score  69.43

PubMed score by year
PubTator Score  22.87

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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