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Tbio
ENO4
Enolase 4

Protein Summary
Description
May be required for sperm motility and function.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341276
  • ENSP00000345555
  • ENSG00000188316
  • ENST00000369207
  • ENSP00000358208
  • ENST00000409522
  • ENSP00000387194

Symbol
  • C10orf134
  • C10orf134
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
virus perturbation
0.64
microRNA
0.6
tissue sample
0.54
cell line
0.46


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.97   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 79   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.97   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 79   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (82)
PKLR
Tbio
Family:  Kinase
Novelty:  0.00268398
Score:  0.987
Data Source:  STRINGDB
PKM
Tchem
Family:  Kinase
Novelty:  0.00076567
Score:  0.982
Data Source:  STRINGDB
GPI
Tbio
Family:  Enzyme
Novelty:  0.00095404
Score:  0.956
Data Source:  STRINGDB
PCK1
Tbio
Family:  Kinase
Novelty:  0.0033726
Score:  0.936
Data Source:  STRINGDB
PCK2
Tbio
Family:  Kinase
Novelty:  0.0035563
Score:  0.933
Data Source:  STRINGDB
MINPP1
Tbio
Family:  Enzyme
Novelty:  0.02584444
Score:  0.9
Data Source:  STRINGDB
TPI1
Tbio
Family:  Enzyme
Novelty:  0.00074652
Score:  0.899
Data Source:  STRINGDB
H6PD
Tbio
Novelty:  0.00366637
Score:  0.889
Data Source:  STRINGDB
TALDO1
Tbio
Family:  Enzyme
Novelty:  0.00208619
Score:  0.875
Data Source:  STRINGDB
PGAM2
Tbio
Family:  Enzyme
Novelty:  0.02438933
Score:  0.868
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Find Similar Targets
Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Glycolysis / Gluconeogenesis
KEGG
HIF-1 signaling pathway
KEGG
RNA degradation
KEGG
Carbon metabolism
KEGG
Metabolic pathways
Name
Explore in Pharos
Explore in Source
Glycolysis / Gluconeogenesis
HIF-1 signaling pathway
RNA degradation
Carbon metabolism
Metabolic pathways
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
1
2
0
15.9
80.3
cup-to-disc ratio measurement
3
2
3
69.6
body mass index
3
1
3
63.7
smoking status measurement
2
1
2
61.4
systolic blood pressure
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cortical surface area measurement
0
15.9
80.3
cup-to-disc ratio measurement
3
69.6
body mass index
3
63.7
smoking status measurement
2
61.4
systolic blood pressure
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
enolase 4
VGNC:12322
742215
Macaque
enolase family member 4
700522
Mouse
MGI:2441717
226265
Rat
RGD:1308333
292138
Dog
enolase 4
VGNC:40368
477832
Species
Name
OMA
EggNOG
Inparanoid
Chimp
enolase 4
Macaque
enolase family member 4
Mouse
Rat
Dog
enolase 4
Publication Statistics
PubMed Score 16.97
PubMed score by year
PubTator Score 0.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title